Role of relaxin in diastasis of the pubic symphysis peripartum  被引量:4

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作  者:Yan Wang Yong-Qiang Li Mei-Rong Tian Nan Wang Zun-Cheng Zheng 

机构地区:[1]Rehabilitation Medicine,Taian City Central Hospital,Taian 271000,Shandong Province,China [2]Department of Otolaryngology,Taian City Central Hospital,Taian 271000,Shandong Province,China [3]Department of Obstetrics,Taian City Central Hospital,Taian 271000,Shandong Province,China [4]Rehabilitation Centre,Qingdao Fuwai Cardiovascular Hospital,Qingdao 266034,Shandong Province,China [5]Department of Rehabilitation,Taian City Central Hospital,Taian 271000,Shandong Province,China

出  处:《World Journal of Clinical Cases》2021年第1期91-101,共11页世界临床病例杂志

基  金:The Science and Technology Development Plan of Taian,No.2018NS0203.

摘  要:BACKGROUND Separation of the pubic symphysis can occur during the peripartum period.Relaxin(RLX)is a hormone primarily secreted by the corpus luteum that can mediate hemodynamic changes during pregnancy as well as loosen the pelvic ligaments.However,it is unknown whether RLX is associated with peripartum pubic symphysis separation and if the association is affected by other factors.AIM To study the association between RLX and peripartum pubic symphysis separation and evaluate other factors that might affect this association.METHODS We performed a cross-sectional study of pregnant women between April 2019 and January 2020.Baseline demographic characteristics,including gestational age,weight,neonatal weight,delivery mode and duration of the first and second stages of labor,were recorded.The clinical symptoms were used as a screening index during pregnancy,and the patients with pubic symphysis and inguinal pain were examined by color Doppler ultrasonography to determine whether there was pubic symphysis separation.Serum RLX concentrations were evaluated 1 d after delivery using an enzyme-linked immunosorbent assay,and pubic symphysis separation was diagnosed based on postpartum X-ray examination.We used an independent-sample t test to analyze the association between serum RLX levels and peripartum pubic symphysis separation.Multivariate regression analysis was used to evaluate whether the association between RLX and peripartum pubic symphysis separation was confounded by other factors,and the association between RLX and the severity of pubic symphysis separation was also assessed.We used Pearson correlation analysis to determine the factors related to RLX levels as well as the correlation between the degree of pubic symphysis separation and activities of daily living(ADL)and pain.RESULTS A total of 54 women were enrolled in the study,with 15 exhibiting(observational group)and 39 not exhibiting(control group)peripartum pubic symphysis separation.There were no statistically significant differences in terms of maternal

关 键 词:PREGNANCY Pubic symphysis separation RELAXIN Neonatal weight Crosssectional study Activities of daily living 

分 类 号:R714.6[医药卫生—妇产科学]

 

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