This work was funded by the Medical and Health Science and Technology Program of Zhejiang Province(2021KY813);the National Natural Science Foundation of China(82174095);the National Natural Science Foundation of Zhejiang Province(LZ22H290001).
Cancer-associated fibroblasts(CAFs)are one of the most abundant stromal cells in the tumor microenvironment which mediate desmoplastic response and are the primary driver for an immunosuppressive microenvironment,lead...
The Science and Technology Development Plan of Taian,No.2018NS0203.
BACKGROUND Separation of the pubic symphysis can occur during the peripartum period.Relaxin(RLX)is a hormone primarily secreted by the corpus luteum that can mediate hemodynamic changes during pregnancy as well as loo...
supported by grants from the National Natural Science Foundation of China 81872915(MWW),81573479(DHY),and 81773792(DHY);the National Science&Technology Major Project"Key New Drug Creation and Manufacturing Program" of China(2018ZX09735-001 to MWW,2018ZX09711002-002-005 to DHY and 2018ZX09711002-002-011 to QL);the National Key R&D Program of China 2018YFA0507000(MWW);the Novo Nordisk-CAS Research Fund(NNCAS-2017-1-CC to DHY)。
Relaxin/insulin-like family peptide receptor 4(RXFP4)is a class A G protein-coupled receptor(GPCR),and insulin-like peptide 5(INSL5)is its endogenous ligand.Although the precise physiological role of INSL5/RXFP4 remai...