结肠镜检查前肠道准备质量影响因素的Meta分析  

Influencing factors of colonoscopy bowel preparations quality:a Meta⁃analysis

作　　者：王田田 尤丽丽[1] WANG Tiantian;YOU Lili(Chinese Academy of Medical Sciences,Peking Union Medical College Hospital,Beijing 100730 China)

机构地区：[1]中国医学科学院北京协和医院,北京100730

出　　处：《护理研究》2021年第2期223-230,共8页Chinese Nursing Research

基　　金：北京协和医院院内课题,编号:XHHLKY201802。

摘　　要：目的:系统评价结肠镜检查前肠道准备质量影响因素。方法:计算机检索the Cochrane Library、PubMed、EMbase、MedLine、中国生物医学文献数据库(CBM)、中国知网(CNKI)、万方数据库(Wanfang Data)和维普数据库(VIP)中与肠道准备质量影响因素相关的研究,检索时限均为建库至2019年12月31日。由2名研究者筛选文献、提取资料,并对其进行质量评价。采用RevMan 5.3软件进行Meta分析。结果:共纳入19篇文献。Meta分析结果显示:年龄>60岁的人群肠道准备质量低于年龄≤60岁的人群[OR=0.55,95%CI(0.41,0.72),P<0.0001],男性肠道准备质量低于女性[OR=0.42,95%CI(0.29,0.60),P<0.00001],体质指数(BMI)≥30 kg/m2人群肠道准备质量低于BMI<30 kg/m2人群[OR=0.91,95%CI(0.84,0.99),P=0.02],有慢性便秘的人群肠道准备质量低于无慢性便秘的人群[OR=0.47,95%CI(0.27,0.81),P=0.007],末次排便为非清水样便的人群肠道准备质量低于末次排便为清水样便的人群[OR=0.37,95%CI(0.20,0.68),P=0.001],合并糖尿病的人群肠道准备质量低于未合并糖尿病的人群[OR=0.34,95%CI(0.17,0.69),P=0.003],有阑尾切除术史的人群肠道准备质量低于无阑尾切除术史的人群[OR=0.56,95%CI(0.36,0.87),P=0.009],使用抗抑郁药物的人群肠道准备质量低于未使用抗抑郁药物的人群[OR=0.32,95%CI(0.29,0.34),P<0.00001]。敏感性分析结果表明Meta分析结果具有稳定性。结论:当前证据显示,年龄、性别、BMI、慢性便秘、末次排便性状、合并糖尿病、阑尾切除术史及抗抑郁药物是肠道准备质量的影响因素。Objective:To systematically evaluate the influencing factors of colonoscopy bowel preparations quality.Methods:Researches on influencing factors of colonoscopy bowel preparations quality were retrieved from the Cochrane Library,PubMed,EMbase,MedLine,CBM,CNKI,Wanfang Data and VIP. The retrieval period was from establishment of databases to 31 December,2019. The literature screening,data extraction and quality evaluation were completed by two researchers. And RevMan 5. 3 software was used for Metaanalysis.Results:A total of 19 literatures were included. Meta-analysis results showed that:people aged>60 years old had lower colonoscopy bowel preparations quality than people age≤60 years old[OR=0. 55,95%CI(0. 41,0. 72),P<0. 000 1],males had lower colonoscopy bowel preparations quality than females[OR=0. 42,95%CI(0. 29,0. 60),P<0. 000 01],people body mass index(BMI)≥30 kg/m^2 had lower colonoscopy bowel preparations quality than people BMI<30 kg/m^2[OR=0. 91,95%CI(0. 84,0. 99),P=0. 02],people with chronic constipation had lower colonoscopy bowel preparations quality than people without chronic constipation[OR=0. 47,95%CI(0. 27,0. 81),P=0. 007],people without watery diarrhea had lower colonoscopy bowel preparations quality than people with watery diarrhea[OR=0. 37,95%CI(0. 20,0. 68),P=0. 001],people with diabetes had lower colonoscopy bowel preparations quality than people without diabetes[OR=0. 34,95%CI(0. 17,0. 69),P=0. 003],people with history of appendectomy had lower colonoscopy bowel preparations quality than people without history of appendectomy[OR=0. 56,95%CI(0. 36,0. 87),P=0. 009],people taking antidepressants had lower colonoscopy bowel preparations quality than people not taking antidepressants[OR=0. 32,95%CI(0. 29,0. 34),P<0. 000 01]. The sensitivity analysis results showed that the Meta-analysis results was stable.Conclusions:Current evidence showed that age,gender,BMI,chronic constipation,characteristic of last bowel movement,diabetes,history of appendectomy,and antidepressants were influencing factors

关 键 词：结肠镜检查 肠道准备质量 影响因素 年龄 便秘 糖尿病 META分析 循证护理 

分 类 号：R574.62[医药卫生—消化系统]