膳食红肉摄入与2型糖尿病并发冠心病的相关性研究  

Correlation between dietary red meat intake and coronary heart disease in type 2 diabetic patients

作　　者：陈洪恩 周娟 曾志伟 彭晓琳 王长义 CHEN Hong-en;ZHOU Juan;ZENG Zhi-wei;PENG Xiao-lin;WANG Chang-yi(Nanshan Centre for Chronic Disease Control,Shenzhen 518054,China;School of Public Health,Huazhong University of Science&Technology)

机构地区：[1]深圳市南山区慢性病防治院,广东深圳518054 [2]华中科技大学公共卫生学院

出　　处：《华南预防医学》2020年第6期593-596,共4页South China Journal of Preventive Medicine

基　　金：深圳市南山区科技局资助项目(南科研卫2017057号);深圳市医疗卫生三名工程(SZSM201803080)。

摘　　要：目的探讨2型糖尿病患者(T2DM)膳食红肉摄入量与并发冠心病(CHD)的关系。方法随机选取深圳市南山区T2DM并发CHD的患者为病例组,以年龄±2岁的原则1∶1配对无CHD的T2DM患者为对照组。采用自制问卷及简化版食物频数问卷对所有参与者进行调查。采用条件Logistic回归对膳食红肉摄入量与T2DM并发CHD进行相关性分析。结果本研究纳入病例和对照各120例,病例组患者人均红肉摄入量中位数为50.00(21.43,100.00)g/d,对照组为42.86(21.43,50.00)g/d,差异有统计学意义(P<0.05)。条件Logistic回归结果显示,T2DM合并CHD的OR值随着膳食红肉摄入量的增加而增加(P线性<0.05)。在校正多种混杂变量后,T2DM患者红肉摄入量为25~50、>50 g/d并发CHD的风险分别是膳食红肉摄入量<25 g/d的2.01倍(95%CI:0.77~5.22)和6.76倍(95%CI:1.55~29.50)。结论T2DM患者膳食红肉摄入量>50 g/d可能是并发CHD的危险因素。Objective To investigate the correlation between dietary red meat intake and coronary heart disease(CHD)in patients with type 2 diabetes mellitus(T2 DM).Methods Patients of T2 DM complicated with CHD in Nanshan District,Shenzhen were randomly selected as the case group and patients of T2 DM without CHD as the control group.Two groups were matched by age(±2 years)at a 1∶1 ratio.Self-made questionnaire and simplified food frequency questionnaire were used to investigate all the subjects.Conditional logistic regression was used to analyze the relationship between dietary red meat consumption and T2 DM complicated with CHD.Results A total of 120 patients in the case group and120 in the control group were investigated.The median of red meat intakes was 50.00(21.43,100.00)g per day in the case group and 42.86(21.43,50.00)g per day in the control group(P<0.05).Conditional logistic regression showed that the OR of T2 DM combined with CHD increased with the increase of dietary red meat intake(Ptrend<0.05).After adjusting for confounding variables,the risks of CHD in T2 DM patients with red meat intake of 25-50 g per day and>50 g per day were2.01 times(95%CI:0.77-5.22)and 6.76 times(95%CI:1.55-29.50)that of the patients with red meat intake<25 g per day,respectively.Conclusion Dietary red meat intake of greater than 50 g per day may be a risk factor for CHD in T2 DM patients.

关 键 词：2型糖尿病 冠心病 红肉摄入 

分 类 号：R151.41[医药卫生—营养与食品卫生学] R153.9[医药卫生—公共卫生与预防医学]