自制抗反流超长胆道塑料支架在恶性胆道梗阻中的应用价值研究  

Research on the application value of self-made anti-reflux super-long biliary tract plastic stent in malignant biliary tract obstruction

作　　者：郑重 陈洽铭 张卓敏[1] ZHENG Zhong;CHEN Qiaming;ZHANG Zhuomin(DepartmentⅣof Surgery,Puning People's Hospital,Guangdong,Puning 515300,China)

机构地区：[1]广东省普宁市人民医院外四科,广东普宁515300

出　　处：《中国医药科学》2020年第24期198-200,共3页China Medicine And Pharmacy

基　　金：广东省揭阳市科技计划项目(2017YL039)。

摘　　要：目的探讨自制抗反流超长胆道塑料支架在恶性胆道梗阻中的应用价值。方法选取2018年1月~2019年12月在本院无法外科手术切除的恶性胆道梗阻患者60例,随机分为试验组(n=30)和对照组(n=30),对照组经内镜逆行性胰胆管造影术中置入普通塑料支架,试验组术中给予抗反流超长胆道塑料支架治疗。检测两组肝功能,并记录住院时间及术后支架通畅期。观察患者术后支架反流、并发症及生存期情况。结果术后两组肝功能水平明显降低,且试验组明显低于对照组,差异有统计学意义(P<0.05)。试验组住院时间、术后支架反流率及术后并发症总发生率明显低于对照组,术后支架通畅期及生存期≥30d比例明显高于对照组,差异有统计学意义(P<0.05)。结论自制抗反流超长胆道塑料支架可改善无法外科手术切除的恶性胆道梗阻患者的肝功能,提高患者生活质量。Objective To investigate the application value of self-made anti-reflux super-long biliary tract plastic stent in malignant biliary tract obstruction.Methods A total of 60 patients with malignant biliary tract obstruction who could not be surgically removed in our hospital from January 2018 to December 2019 were selected and were randomly divided into the experimental group(n=30)and the control group(n=30).The control group was implanted with ordinary plastic stent during endoscopic retrograde cholangiopancreatography,while the experimental group was implanted with anti-reflux super-long biliary tract plastic stent during operation.The hepatic functions were detected in both groups,and the hospitalization time and stent patency period after operation were recorded.The postoperative stent reflux,complications and survival time of patients were observed.Results The levels of hepatic functions in the two groups decreased significantly after operation,and the experimental group were significantly lower than those in the control group,with statistically significant differences(P<0.05).The hospitalization time,postoperative stent reflux rate and total postoperative complication rate in the experimental group were significantly lower than those in the control group,while the proportion of stent patency and survival time≥30 days after operation was significantly higher than those in the control group,with statistically significant differences(P<0.05).Conclusion Self-made anti-reflux superlong biliary tract plastic stent can improve the hepatic function and improve the quality of life of patients with malignant biliary tract obstruction that cannot be surgically removed.

关 键 词：恶性胆道梗阻 塑料支架 经内镜逆行性胰胆管造影术 生存期 

分 类 号：R730.5[医药卫生—肿瘤]