低钾型周期性麻痹临床特点及血清肌酸激酶异常分析  

Clinical features of hypokalemic periodic paralysis and analysis of abnormal serum creatine kinase

作　　者：王勇 杨静[1] WANG Yong;YANG Jing(Department of Emergency,the Third Affiliated Hospital of Anhui Medical University,the First People's Hospital of Hefei City,Anhui,Hefei 230061,China)

机构地区：[1]安徽医科大学第三附属医院,合肥市第一人民医院急诊部,安徽合肥230061

出　　处：《中国医药科学》2020年第23期240-242,246,共4页China Medicine And Pharmacy

摘　　要：目的探讨低钾型周期性麻痹(HypoPP)的临床特点及血清肌酸激酶改变。方法选取我院急诊科2008年7月~2016年4月收治的低钾型周期性麻痹住院患者53例,分析临床资料,观察其血清肌酸激酶改变及规律。结果低钾型周期性麻痹多发于中青年男性,表现为肌无力和低血钾,血清肌酸激酶增高占69.8%,血清肌酸激酶升高组病程延长。结论 HypoPP以肌无力伴低钾血症为其临床特点,血清肌酸激酶增高是低钾型周期性麻痹的重要临床特征之一。Objective To investigate the clinical features of hypokalemic periodic paralysis(HypoPP) and changes of serum creatine kinase. Methods A total of 53 inpatients with HypoPP admitted to the emergency department of our hospital from July 2008 to April 2016 were selected. The clinical data were analyzed. Meanwhile, the changes and regularity of serum creatine kinase were observed. Results HypoPP occurred mostly in young and middle-aged men, manifested as myasthenia gravis and hypokalemia. The increase of serum creatine kinase accounted for 69.8%, and the course of disease was prolonged in the group of elevated serum creatine kinase. Conclusion HypoPP is featured by myasthenia with hypokalemia, and the increase of serum creatine kinase is one of the important clinical features of HypoPP.

关 键 词：低钾血症 周期性麻痹 肌酸激酶 临床分析 

分 类 号：R746.3[医药卫生—神经病学与精神病学]