两种方法治疗肌层浸润性膀胱癌的临床疗效分析  

Clinical Efficacy Analysis of Two Methods in the Treatment of Muscular Layer Invasive Bladder Cancer

作　　者：叶超平[1] 柳宏林[1] 尹三省[1] 覃宝笋[1] 莫宏辉[1] YE Chaoping;LIU Honglin;YIN Sansheng;TAN Baoshun;MO Honghui(Nanxishan Hospital of Guangxi Zhuang Autonomous Region,Guilin,Guangxi 541000,China)

机构地区：[1]广西壮族自治区南溪山医院,广西桂林541000

出　　处：《大医生》2020年第20期15-17,共3页Doctor

基　　金：广西壮族自治区卫生厅自筹经费科研课题申请书(合同书)(编号:Z2012241)。

摘　　要：目的对比两种不同方法治疗肌层浸润性膀胱癌的临床效果。方法选取广西壮族自治区南溪山医院2016年3月至2020年5月收治的86例肌层浸润性膀胱癌患者为研究对象,按照随机双盲法分为研究组(43例)与对照组(43例)。研究组采取经尿道手术保留膀胱综合治疗,对照组采取根治性膀胱切除术治疗。对比两组患者的术中失血量、手术时长、恢复进食时间、导尿管留置时间、住院时长、并发症发生率及SF-36评分指标。结果研究组患者的术中失血量、手术时长、恢复进食时间、导尿管留置时间及住院时长均低于对照组(P<0.05);研究组患者的并发症发生率为6.98%,低于对照组的23.26%(P<0.05);治疗前两组患者的各项评分比较均差异无统计学意义(P>0.05),而治疗后研究组患者的SF-36评分均高于对照组(P<0.05)。结论经尿道手术保留膀胱综合治疗肌层浸润性膀胱癌,可减少患者术中的失血量,有效缩短住院时长,防止严重并发症的发生,提升患者的生存质量。Objective To compare the effects of two treatment methods in invasive bladder cancer.Methods A total of 86 patients with muscular-layer invasive bladder cancer treated from March 2016 to May 2020 in Nanxishan Hospital of Guangxi Zhuang Autonomous Region were selected.According to the randomized double-blind method,patients were divided into study group and control group,43 cases in each group.The study group was treated with transurethral operation and bladder retention,and the control group was treated with radical cystectomy.Intraoperative blood loss,duration of surgery,time to recover feeding,catheter indwelling time,length of hospital stay,incidence of complications and SF-36 score were compared between the two groups.Results The intraoperative blood loss,duration of operation,time to recover feeding,catheter indwelling time and length of hospital stay in the study group were all lower than those in the control group(P<0.05).The complication rate of the study group was 6.98%,lower than that of the control group(23.26%,P<0.05).Before treatment,there was no statistically significant difference in scores between the two groups(P>0.05),while SF-36 scores of patients in the study group were higher than those in the control group after treatment(P<0.05).Conclusion Transurethral surgery with bladder preservation for the treatment of muscular invasive bladder cancer has a satisfactory clinical effect,which can reduce intraoperative blood loss,effectively shorten the length of hospital stay,prevent the occurrence of serious complications,and improve the quality of life of the patients.It is worthy of clinical application.

关 键 词：肌层浸润 膀胱癌 根治性 膀胱切除术 经尿道手术 保留膀胱 

分 类 号：R73[医药卫生—肿瘤]