IOL Master 700测量白内障眼球生物参数的重复性及眼轴长度检出率  

Repeatability of IOL Master 700 in ocular biometrics and axial length detection rate in cataract eyes

作　　者：彭悦 廖萱[1,2] 兰长骏[1,2] 刘波[1,2,4] 谭青青 Yue Peng;Xuan Liao;Chang-Jun Lan;Bo Liu;Qing-Qing Tan(Department of Ophthalmology,Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,Sichuan Province,China;Department of Ophthalmology&Optometry,North Sichuan Medical College,Nanchong 637000,China;Department of Ophthalmology,Pengzhou People's Hospital,Pengzhou 611930,Sichuan Province,China;Department of Ophthalmology,Shuangliu District Chinese Medicine Hospital,Chengdu 610200,Sichuan Province,China)

机构地区：[1]川北医学院附属医院眼科,中国四川省南充市637000 [2]川北医学院眼视光学系,中国四川省南充市637000 [3]中国四川省彭州市人民医院眼科,611930 [4]双流区中医医院眼科,中国四川省成都市610200

出　　处：《国际眼科杂志》2021年第2期355-359,共5页International Eye Science

基　　金：四川省卫计委重点课题项目(No.18ZD022);南充市校合作重大攻关项目(No.18SXHZ0492)。

摘　　要：目的:评价基于扫频光相干断层扫描(SS-OCT)技术的IOL Master 700生物测量仪测量白内障眼球生物参数的重复性,以及与部分相干光干涉生物测量仪IOL Master 500测量眼轴长度(AL)的一致性和检出率。方法:采用横断面研究方法,共纳入2018-07/09门诊就诊的白内障患者133例225眼进行研究。由同一位经验丰富的检查者分别用IOL Master 700和IOL Master 500测量白内障患者眼球生物参数3次,记录AL、角膜曲率(K)、前房深度(ACD)、晶状体厚度(LT)、中央角膜厚度(CCT)、白到白角膜直径(WTW)。结果:IOL Master 700测量白内障患者AL、Km、K1、K2、ACD、LT、CCT、WTW的组内标准差(Sw)分别为0.027mm、0.112、0.148、0.162D、0.015、0.010mm、2.355μm、0.134mm,相对变异系数(CoV)为0.115%~1.162%,组内相关系数(ICC)≥0.923,其中AL的ICC最大为1.000,所有参数均有较高的重复性。IOL Master 700与IOL Master 500测量的AL分别为23.805±2.162、23.782±2.162mm,二者差值为0.023±0.010mm(t=33.645,P<0.001);95%一致性限(95%LoA)为0.003~0.043mm,两仪器测量的AL呈高度正相关(r=1.000,P<0.001),一致性较好。IOL Master 700的AL检出率为93.8%(211/225),IOL Master 500为87.6%(197/225)(χ^2=5.147,P=0.023)。结论:IOL Master 700测量白内障患者眼球生物参数AL、Km、K1、K2、ACD、LT、CCT、WTW均有较高的重复性,其中AL重复性最好;与IOL Master 500测量AL参数有较好一致性,但IOL Master 700对混浊严重及后囊下白内障AL检出率更高。AIM:To evaluate the repeatability of a swept-source optical coherence tomography(SS-OCT)based biometer-IOL Master 700 in ocular biometrics in cataract eyes,and to investigate its agreement with a partially coherent optical interference based biometer-IOL Master 500.This study was also designed to compare the detection rate of the axial length(AL)measured by the two biometers.METHODS:A total of 225 eyes of 133 cataract patients were included in this cross-sectional study from July to September 2018.Ocular biometric parameters including AL,keratometry(K),anterior chamber depth(ACD),lens thickness(LT),central corneal thickness(CCT)and white to white(WTW)were measured for each participant by both IOL Master 700 and IOL Master 500.RESULTS:The IOL Master 700 measured Sw of AL,Km,K1,K2,ACD,LT,CCT,WTW in cataract patients were 0.027mm,0.112D,0.148D,0.162D,0.015mm,0.010mm,2.355μm and 0.134mm,CoV was 0.115%-1.162%,ICC≥0.923,the maximum ICC of AL is 1.000,and all measurements had high repeatability.The AL measured by IOL Master 700 and IOL Master 500 were(23.805±2.162)mm and(23.782±2.162)mm respectively,the difference was statistically significant(t=33.645,P<0.001).However,the 95%LoA was 0.003mm-0.043mm,and the AL measured by the two biometers was significantly correlated(r=1.000,P<0.001)with good agreement.The AL detection rates were 93.8%(211/225)for IOL Master 700 and 87.6%(197/225)for IOL Master 500,the difference was statistically significant(χ^2=5.147,P=0.023).CONCLUSION:IOL Master 700 demonstrates excellent repeatability in ocular biometric measurements including AL,Km,K1,K2,ACD,LT,CCT and WTW for cataract patients,especially in AL measurement.IOL Master 700 is in good agreement with IOL Master 500 in measuring AL,however the IOL Master 700 has a higher detection rate for AL in patients with severe opacity and subcapsular opacity in their lens.

关 键 词：生物测量/眼 扫频光相干断层扫描 重复性 一致性 检出率 

分 类 号：R776.1[医药卫生—眼科]