血清甘胆酸检测在肝病诊断中的应用价值分析  

Analysis of application value of serum glycocholic acid detection in diagnosis of liver disease

作　　者：夏素娟 Xia Sujuan(Department of Laboratory,the People's Hospital of Zouping City,Shandong Province,Shandong Binzhou 256200)

机构地区：[1]山东省邹平市人民医院检验科,山东滨州256200

出　　处：《中国社区医师》2021年第3期139-140,共2页Chinese Community Doctors

摘　　要：目的:为了讨论在肝病诊断中应用哪种检测方式可以使此次研究更加有意义和应用价值,本文选择采用血清甘胆酸检测方法诊断肝病。方法:选取2019年8月-2020年4月在我院进行肝病诊断的20例肝炎患者、10例肝硬化患者、12例肝癌患者、8例其他肝胆疾病患者,总共50例患者作为观察组。另外选取同期在本医院进行体检的80例健康人作为研究对象。分别检测所有人的血清甘胆酸水平值,并根据最终结果来分析血清甘胆酸在肝病患者诊断中的应用价值。结果:肝炎血清甘胆酸值和对照组(健康人)对比为(27.6±4.6)mg/L vs(1.4±0.1)mg/L,肝硬化血清甘胆酸值和对照组对比为(48.4±3.1)mg/L vs(1.4±0.1)mg/L,肝癌血清甘胆酸值和对照组对比为(51.7±4.9)mg/L vs(1.4±0.1)mg/L,其他肝胆疾病血清甘胆酸值和对照组对比为(65.4±5.1)mg/L vs(1.4±0.1)mg/L。研究发现观察组血清甘胆酸数值明显高于对照组,组间数据差异明显,具有统计学意义(P<0.05)。结论:在肝病诊断中应用血清甘胆酸指标检测,可以检测出肝细胞和肝胆系统破损的程度,对于疾病的诊断、治疗和预后具有重要意义。Objective:In order to discuss which detection method to use in the diagnosis of liver disease can make this study more meaningful and practical,this article chooses the serum glycocholic acid detection method.Methods:From August 2019 to April 2020,20 patients with hepatitis,10 patients with liver cirrhosis,12 patients with liver cancer,8 patients with other hepatobiliary diseases who were diagnosed with liver disease in our hospital from August 2019 to April 2020 were selected as the observation group.In addition,80 healthy people who underwent physical examination in our hospital during the same period were selected as the research objects.The serum glycocholic acid levels of all people were detected respectively,and the application value of serum glycocholic acid in the diagnosis of liver disease patients was analyzed according to the final results.Results:The serum glycocholic acid value of hepatitis and the control group(healthy people)is(27.6±4.6)mg/Lvs(1.4±0.1)mg/L,and the serum glycocholic acid value of liver cirrhosis is(48.4±3.1)mg compared with the control group./Lvs(1.4±0.1)mg/L,the serum glycocholic acid value of liver cancer compared with the control group is(51.7±4.9)mg/Lvs(1.4±0.1)mg/L,the serum glycocholic acid value of other hepatobiliary diseases and the control group The contrast is(65.4±5.1)mg/L vs(1.4±0.1)mg/L.The study found that the serum glycocholic acid value of the observation group was significantly higher than that of the control group,and the data difference between the groups was significant,which was statistically significant(P<0.05).Conclusion:The detection of serum glycocholic acid in the diagnosis of liver disease can detect the degree of hepatocyte and hepatobiliary system damage,which is of great significance for the diagnosis,treatment and prognosis of the disease.

关 键 词：血清甘胆酸 肝病 鉴别诊断 应用价值 

分 类 号：R575[医药卫生—消化系统] R446.1[医药卫生—内科学]