生化检验项目在肝硬化疾病诊断中的临床价值  

Clinical Value of Biochemical Test in Diagnosis of Liver Cirrhosis

作　　者：孟宪良 MENG Xianliang(Donggang Central Hospital,Dandong 118300,China)

机构地区：[1]东港市中心医院,辽宁丹东118300

出　　处：《中国医药指南》2020年第35期113-114,共2页Guide of China Medicine

摘　　要：目的探究在肝硬化疾病诊断中应用生化检验项目的临床价值。方法本研究从本院肝硬化患者中选取样本,总例数为100例,研究时间始于2018年2月,止于2019年2月,依据诊断方案的异同进行分组,试验组予以生化检验项目,并选取同期100名健康体检者作为对照组,对比两组受检者检验结果。结果试验组患者直接胆红素(DBIL)、总胆红素(TBIL)、γ-谷氨酰转移酶(γ-GT)、丙氨酸转氨酶(ALT)、谷草转氨酶(AST)、碱性磷酸酶(ALP)指标相对对照组而言有着明显的升高,统计差异值合理(P<0.05);试验组患者胆碱酯酶(CHE)、总蛋白(TP)、白蛋白(ALB)指标明显较低,且低于对照组,统计差异值合理(P<0.05)。结论在肝硬化疾病诊断中应用生化检验项目,能明确患者的肝功能、蛋白指标,对肝硬化疾病有着较高的特异性,能为基层医疗机构临床诊断提供重要的参考依据。Objective To investigate the clinical value of biochemical test in diagnosis of liver cirrhosis.Methods This study selected samples from patients with cirrhosis in our hospital.The total number of cases is 100.The research began in February 2018,in February 2019.According to the similarities and differences of the diagnostic scheme.The test group gave biochemical tests.And selected 100 health check-ups as control group.The results of the two groups were compared.Results The indexes of direct bilirubin(DBIL),total bilirubin(TBIL),γ-glutamyltransferase(γ-GT),alanine aminotransferase(ALT),alanine aminotransferase(AST)and alkaline phosphatase(ALP)in the experimental group were significantly higher than those in the control group.The statistical difference was reasonable(P<0.05).The indexes of cholinesterase(CHE),total protein(TP)and albumin(ALB)were significantly lower in the experimental group,and lower than the control group,and the statistical difference was reasonable(P<0.05).Conclusion Application of biochemical tests in the diagnosis of cirrhosis,can define the liver function,protein index of the patient,high specificity for cirrhosis,can provide important reference for clinical diagnosis in primary medical institutions.

关 键 词：肝硬化 诊断方式 慢性疾病 消化系统 生化检验 

分 类 号：R574.2[医药卫生—消化系统] R446.1[医药卫生—内科学]