中药和食品中大豆异黄酮分析方法的研究进展  

Research advances on analytical methods of soybean isoflavones in traditional Chinese medicines and foods

作　　者：徐硕[1] 金鹏飞[1] 徐文峰[1] 吴学军[1] 姜文清[1] XU Shuo;JIN Pengfei;XU Wenfeng;WU Xuejun;JIANG Wenqing(Department of Pharmaceutical Science,Beijing Hospital,National Center of Gerontology,Institute of Geriatric Medicine,Chinese Academy of Medical Sciences,Beijing Key Laboratory of Drug Clinical Risk and Personalized Medication Evaluation,Beijing 100730,China)

机构地区：[1]北京医院药学部,国家老年医学中心,中国医学科学院老年医学研究院,药物临床风险与个体化应用评价北京市重点实验室,北京100730

出　　处：《西北药学杂志》2021年第1期166-169,共4页Northwest Pharmaceutical Journal

基　　金：国家自然科学基金青年科学基金项目(编号:81303216)。

摘　　要：目的了解中药和食品中大豆异黄酮分析方法的研究进展。方法通过查阅相关文献并归纳总结,综述近年来各种分析技术在中药和食品中大豆异黄酮分析中的应用。结果大豆异黄酮的分析方法包括薄层扫描法、紫外分光光度法、高效液相色谱(HPLC)法、超高效液相色谱(UPLC)法和液相色谱-质谱联用(LC-MS)法,其中HPLC法被广泛应用于大豆异黄酮的测定。结论大豆异黄酮的分析方法取得了一定进展,大豆异黄酮作为重要的生物活性成分,对其分析检测方法的进一步探讨具有重要意义。Objective To review the research progress of analytical methods of soybean isoflavones in traditional Chinese medicines and foods.Methods The application of various analytical techniques in analysis of soybean isoflavones in traditional Chinese medicines and foods was reviewed by consulting relevant literature and summarizing.Results The analytical methods of soybean isoflavones include thin layer chromatogramphy scanning,UV spectrophotometry,high performance liquid chromatography(HPLC),ultra performance liquid chromatography(UPLC)and liquid chromatography-mass spectrometry(LC-MS).Among them,HPLC method was widely used in the determination of soybean isoflavones.Conclusion Much progress has been made in analytical methods of soybean isoflavones in traditional Chinese medicines and foods.As important bioactive components,it is of great significance to further explore the analytical methods of soybean isoflavones.

关 键 词：大豆异黄酮 分析方法 含量测定 中药 食品 

分 类 号：R917[医药卫生—药物分析学]