大动脉粥样硬化型脑梗死与穿支动脉疾病型脑梗死的临床特点对比  

Comparison of clinical characteristics between cerebral infarction with great atherosclerosis and cerebral infarction with perforator artery disease

作　　者：刘福达[1] 李超英[1] 温骏 陈世文[1] LIU Fu-da;LI Chao-ying;WEN Jun(Department of NeurologyⅡ,Jiangmen Cental Hospital,Jiangmen 529030,China)

机构地区：[1]广东省江门市中心医院神经内科二区,广东江门529030

出　　处：《吉林医学》2021年第2期305-307,共3页Jilin Medical Journal

摘　　要：目的:研究大动脉粥样硬化型脑梗死与穿支动脉疾病型脑梗死的临床特点。方法:选择114例脑梗死患者展开研究,按照中国缺血性卒中亚型的病因分型分为两组,即大动脉粥样硬化型脑梗死(LAA)组60例、穿支动脉疾病型脑梗死(PAD)组54例。将两组的一般资料、基础疾病情况、实验室检查指标、发病部位、转归情况进行比对。结果:LAA组的吸烟、饮酒比例高于PAD组,差异具有统计学意义(P<0.05);LAA组的糖尿病发病率及一氧化氮水平低于PAD组,冠心病、脂代谢异常发生率以及血浆氧化低密度脂蛋白、循环内皮细胞计数高于PAD组,差异具有统计学意义(P<0.05);LAA组的侧脑室旁、皮层、小脑、分水岭发病率与PAD组进行比较,差异有统计学意义(P<0.05);两组患者的NIHSS评分、mRS评分进行比较,差异无统计学意义(P>0.05)。结论:大动脉粥样硬化型脑梗死、穿支动脉疾病型脑梗死的临床特点存在差异,有利于临床实施针对性的防治措施。Objective To study the clinical characteristics of large atherosclerotic cerebral infarction and perforator artery disease cerebral infarction.Method 114 patients with cerebral infarction admitted to our hospital were included in this study.According to the etiology of the subtype of ischemic stroke in China,they were divided into two groups,namely,60 patients with large atherosclerotic cerebral infarction(LAA)group and 54 patients with perforator artery disease cerebral infarction(PAD)group.The general data,basic diseases,biochemical indexes,disease location and prognosis of the two groups were compared.Results The proportion of smoking and drinking in group LAA was higher than that in group PAD,the difference was statistically significant(P<0.05);the incidence and the level of nitric oxide in group LAA were lower than those in group PAD;the incidence of coronary heart disease,abnormal lipid metabolism and the number of plasma oxidized low density lipoprotein and circulating endothelial cells were higher than those in group PAD(P<0.05);The incidence of cerebellar and watershed differences was significantly different from those of group PAD(P<0.05).There was no significant difference in NIHSS score and mRS score between the two groups(P>0.05).Conclusion There are differences in the clinical characteristics between the two types of cerebral infarction,which is conducive to the clinical implementation of targeted prevention and treatment measures.

关 键 词：大动脉粥样硬化型脑梗死 穿支动脉疾病型脑梗死 特点 

分 类 号：R743.33[医药卫生—神经病学与精神病学]