音乐疗法在90例正颌术后带管患者镇静镇痛中的效果评价  

Evaluation of the effect of music therapy on sedation and analgesia in 90 patients with endotracheal intubation after orthognathic surgery

作　　者：辛志祥[1] 孙璐璐[1] 林宇[1] 吕翔[1] XIN Zhi-xiang;SUN Lu-lu;LIN Yu;LYU Xiang(Department of Anesthesiology,Shanghai Ninth People's Hospital,Shanghai Jiao Tong University School of Medicine.Shanghai 200011,China)

机构地区：[1]上海交通大学医学院附属第九人民医院麻醉科,上海200011

出　　处：《中国口腔颌面外科杂志》2021年第1期49-51,共3页China Journal of Oral and Maxillofacial Surgery

摘　　要：目的 :探讨音乐疗法在正颌术后带管患者镇静镇痛中的有效性和安全性。方法 :将择期行正颌手术的90例患者随机分为3组,每组各30例。A、B组分别给予0.4、0.8μg/(kg·h)右美托咪定镇静镇痛,C组则给予右美托咪定0.4μg/(kg·h)+音乐疗法。分别记录3组患者的一般情况,观察术毕入监护室后3 h(T1)、6 h(T2)、9 h(T3)、12 h(T4)平均血压、心率以及镇静镇痛评分,比较3组患者不良反应的发生率。采用GraphPad Prism 5软件包进行数据分析。结果:A、C组在T2、T3、T4时间点平均血压均高于B组,A、C组心率在各时间点均显著高于B组(P<0.05)。B、C组Ramsay镇静评分在各时间点均显著高于A组而VAS疼痛评分显著低于A组(P<0.05)。C组患者心动过缓、低血压发生率显著低于B组(P<0.05)。结论:音乐疗法可减少正颌术后带管患者右美托咪定使用量,具有辅助镇静镇痛作用,效果确切,可减少药物不良反应发生率。PURPOSE: To investigate the efficacy and safety of music therapy in sedation and analgesia of patients with endotracheal intubation after orthognathic surgery. METHODS: Ninety patients undergoing orthognathic surgery were randomly divided into 3 groups, 30 in each group. Patients in groups A and B received treatment of sedation and analgesia with dexmedetomidine at 0.4 μg/(kg·h) and 0.8 μg/(kg·h), respectively;while patients in group C were given dexmedetomidine with 0.4 μg/(kg·h) + music therapy. The general conditions were recorded and average blood pressure, heart rate, sedation and analgesia scores at 3 h(T1), 6 h(T2), 9 h(T3) and 12 h(T4) in ICU after operations were also observed. The incidence of adverse reactions was compared among the 3 groups. The data were analyzed using GraphPad Prism 5 software package. RESULTS:The mean blood pressure of group A and group C was significantly higher than that of group B at T2, T3 and T4 time points,the heart rate of patients in group A and group C was significantly higher than that of patients in group B at each time point(P<0.05). Ramsay sedation score of patients in group B and group C was significantly higher than that of group A at all time points, while VAS pain score was significantly lower than that of group A(P <0.05). The incidence of bradycardia and hypotension in group C was significantly lower than that in group B(P<0.05). CONCLUSIONS: Music therapy can reduce the use of dexmedetomidine in patients with endotracheal intubation after orthognathic surgery. It has definite effect of assistant sedation and analgesia, and can reduce the incidence of adverse drug reactions.

关 键 词：音乐疗法 正颌外科 镇静镇痛 应激反应 

分 类 号：R782.05[医药卫生—口腔医学]