衰弱合并脑血管病研究进展  

Research progress of frailty complicated with cerebrovascular disease

作　　者：赵瑞雪[1] 马雅军 李晓东[1] 王笑峰 蒋晓燕 李淑娟[1] ZHAO Rui-xue;MA Ya-jun;LI Xiao-dong;WANG Xiao-feng;JIANG Xiao-yan;LI Shu-juan(Department of Neurology,Beijing Chao-Yang Hospital,Capital Medical University,Beijing 100020,China;Ministry of Education Key Laboratory of Contemporary Anthropology,Human Phenome Institute,Fudan University,Shanghai 200433,China;Department of Pathology and Pathophysiology,Tongji University School of Medicine,Shanghai 200092,China)

机构地区：[1]首都医科大学附属北京朝阳医院神经内科,100020 [2]复旦大学人类表型组研究院现代人类学教育部重点实验室,上海200433 [3]同济大学医学院病理学与病理生理学系,上海200092

出　　处：《中国现代神经疾病杂志》2021年第1期30-33,共4页Chinese Journal of Contemporary Neurology and Neurosurgery

基　　金：国家重点研发计划项目(项目编号:2018YFC2000400);国家重点研发计划项目(项目编号:2018YFC2002000);国家自然科学基金资助项目(项目编号:81971102)。

摘　　要：衰弱系多系统生理储备和功能下降导致的老年综合征,使老年人对内外环境的应激能力和维持稳态能力下降,并使不良事件风险增加。其中以脑卒中患者衰弱和衰弱前期发生率最高且明显高于非脑卒中患者,而衰弱人群脑血管病患病率亦显著增加且预后不良。本文拟对衰弱与脑血管病之间的潜在关联性进行综述。Frailty is a geriatric syndrome caused by a decrease in multi-system physiological reserve and function,which reduces the elderly’s ability to stress the internal and external environment and maintain homeostasis,and increases the risk of adverse health events.The incidence of frailty and prefrailty in stroke patients is the highest and significantly higher than that in non-stroke patients,while the prevalence of cerebrovascular disease in frailty patients is also significantly increased and the prognosis is worse.This paper intends to review the potential association between frailty and cerebrovascular disease.

关 键 词：蛋白质能量营养不良 卒中 老年人 综述 

分 类 号：R743[医药卫生—神经病学与精神病学]