区段性任脉药物铺灸治疗少弱精子症的临床研究  

Clinical Study on the Effect and Mechanism of the Drug Moxibustion along Sectional Ren Channel on the Semen Parameters of Oligospermia

作　　者：房连强[1] 李星凌[1] 郭勤[1] 刘婧[1] 张全爱[1] FANG Lian-qiang;LI Xing-ling;GUO Qin;LIU Jing;ZHANG Quan-ai(The Third Affiliated Hospital of Zhejiang Chinese Medical University,Hangzhou,310012,China)

机构地区：[1]浙江中医药大学附属第三医院,浙江杭州310012

出　　处：《南京中医药大学学报》2021年第1期36-40,共5页Journal of Nanjing University of Traditional Chinese Medicine

基　　金：浙江省中医药科技计划项目(2019ZB063);浙江省中医药重点学科(浙中医药[2017]105号)。

摘　　要：目的探讨区段性任脉药物铺灸对少弱精子症精液参数的影响和作用机制。方法70例患者随机分为治疗组、对照组,每组35例。对照组口服维生素E胶囊、五子衍宗丸治疗;治疗组在对照组基础上,采用区段性任脉药物铺灸治疗,分别于治疗2个月、3个月,分析治疗前后2组精液参数、精浆超氧化物歧化酶(SOD)活性、丙二醛(MDA)水平及DNA碎片指数(DFI)变化,并评价临床疗效。结果治疗后2组精子浓度、形态明显改善,活力显著增加(P<0.01),治疗组较对照组优势明显(P<0.01);治疗组较对照组能更有效地增加精浆SOD活性、降低MDA水平、降低DFI指数(P<0.01);治疗组临床总有效率为88.57%,高于对照组(P<0.05)。结论区段性任脉药物铺灸能显著降低MDA水平,增加SOD活性,改善DFI,优化精液参数,提高临床疗效。OBJECTIVE To explore the effects and mechanisms of drug moxibustion along the sectional Ren channel on the semen parameters of oligospermia.METHODS 70 patients were randomly divided into the treatment group and the control group,35 cases per group.Vitamin E capsules and Wuzi Yanzong pills were given orally in the control group.Based on the control group,the treatment group adopted the Long-snake drug moxibustion along the sectional Ren channel.Semen parameters,semen superoxide dismutase(SOD)activity,levels of acetaldehyde(MDA),and DNA fragmentation index(DFI)in the two groups were analyzed before and after 2 or 3 months of treatment.Besides,clinical efficacy had been estimated.RESULTS After treatment,sperm concentration and sperm vitality increased significantly in the two groups(P<0.01).The tendencies of increased sperm concentration and improved normal form rate and sperm motility in the treatment group were obvious(P<0.01).Compared with the control group,the treatment group had more effectively increased the SOD activity of the pulp,reduced the level of MDA,and decreased the DFI index(P<0.01).The total clinical efficiency of the treatment group was 88.57%,higher than the control group(P<0.05).CONCLUSION Drug moxibustion along the sectional Ren channel can significantly reduce MDA level,increase SOD activity,improve DFI,optimize semen parameters,and improve clinical efficacy.

关 键 词：铺灸 少弱精子症 任脉 精液参数 

分 类 号：R256.55[医药卫生—中医内科学]