正电子发射断层显像在心脏恶性肿瘤诊断中的临床应用价值  

The clinical application of positron emission tomography in the diagnosis of cardiac malignant tumors

作　　者：陈兰兰 郝珊瑚 张国旭 CHEN Lanlan;HAO Shanhu;ZHANG Guoxu(Department of Nuclear Medicine,the General Hospital of Northern Theater Command,Liaoning Shenyang 110016,China)

机构地区：[1]北部战区总医院核医学科,辽宁沈阳110016

出　　处：《现代肿瘤医学》2021年第4期656-659,共4页Journal of Modern Oncology

基　　金：辽宁省科学技术计划项目(编号:2012225019)。

摘　　要：目的:探讨正电子发射断层显像(PET/CT)在心脏肿瘤诊断中的临床应用价值。方法:回顾性分析2011年1月-2018年12月,在我中心行PET/CT检查的23例心脏肿瘤患者的全身PET/CT的诊断结果,确诊依据为术后病理结果、临床随诊结果证实,评价PET/CT对心脏肿瘤诊断效能。结合影像学特征及SUV_(max)得到PET/CT的诊断结果,与确定诊断进行比较,采用两样本t检验分析数据,分析PET/CT对心脏恶性肿瘤的诊断能力。结果:23例心脏肿瘤患者中,恶性肿瘤19例,原发恶性肿瘤6例,转移瘤13例;良性病例4例。PET/CT显像在心脏良恶性肿瘤诊断灵敏度、特异性、准确率分别为89.5%(17/19)、75.0%(3/4)、87.0%(20/23);恶性肿瘤平均SUV_(max)为14.5±9.7,良性肿瘤SUV_(max)为3.0±2.4,两者比较差异有统计学意义(t=-1.95,P<0.05)。恶性肿瘤PET/CT显像发现全身多部位、多器官转移的16人,改变了临床分期及治疗方案。结论:PET/CT显像对心脏恶性肿瘤的诊断,具有较高的灵敏度和特异性,可为鉴别诊断心脏占位性病变良恶性提供帮助,对肿瘤临床分期及治疗方案的确定具有非常大的指导意义。Objective:To investigate the clinical value of positron emission tomography(PET/CT)in the diagnosis of cardiac tumors.Methods:The PET/CT imaging of 23 patients with cardiac tumors who underwent PET/CT examination from January 2011 to December 2018 was restrospectively analyzed.The diagnostic was based on postoperative pathological findings and clinical follow-up results.The PET/CT diagnostic efficacy of cardiac tumor was evaluated.The SUV max of benign and malignant tumors was compared with the definite diagnosis,and the data was analyzed by two-sample t-test.Results:Among the 23 patients with cardiac tumors,19 were malignant tumors,6 were primary malignant tumors,13 were metastatic tumors,and 4 were benign cases.The sensitivity,specificity and accuracy of PET/CT imaging in benign and malignant neoplasms were 89.5%(17/19),75.0%(3/4),and 87.0%(20/23),respectively.The average SUV max of malignant tumors was 14.5±9.7.The SUV max of benign tumors was 3.0±2.4.There was a significant difference between the two groups(t=-1.95,P<0.05).PET/CT imaging of malignant tumors found that 16 people with multiple parts and multiple organ metastases and changed clinical staging and therapeutic schedule.Conclusion:PET/CT imaging has a high sensitivity and specificity for the diagnosis of cardiac malignant tumors which can help to differentiate the benign and malignant lesions cardiac occupying lesions,and has great guidance for the clinical staging and treatment of tumors.

关 键 词：心脏肿瘤 正电子发射断层显像术 脱氧葡萄糖 体层摄影术 X线计算机 

分 类 号：R732.1[医药卫生—肿瘤]