广州社区居民颈动脉病变流行状况及相关因素分析  

Analysis on the prevalence and related factors of carotid artery disease in Guangzhou community residents

作　　者：梁肖玉[1] 戴颖仪[1] 张竹 闫修魁 林鸿滨[2] 李东仕 涂平忠 焦锐 刘新通[1] 林剑国 LIANG Xiao-yu;DAI Ying-yi;ZHANG Zhu;YAN Xiu-kui;LIN Hong-bin;LI Dong-shi;TU Ping-zhong;JIAO Rui;LIU Xin-tong;LIN Jian-guo(Department of Neurology,the Center for Cerebrorascular Diseases,luangdong Sec-ond Provincial General Hospital)

机构地区：[1]广东省第二人民医院脑血管病中心神经内科,广东广州510317 [2]广东省第二人民医院药学部,广东广州510317

出　　处：《广东医学》2020年第24期2545-2549,共5页Guangdong Medical Journal

基　　金：广东省医学科研基金资助项目(C2019056);广东省第二人民医院引进人才启动基金(YY2017-002)。

摘　　要：目的探讨广州社区居民颈动脉病变流行率及相关因素。方法对广州市35个社区35岁以上的居民进行脑血管病相关因素现况调查,调查手段包括面对面问卷,现场体检,睡眠心理测试,心电图,腹部、妇科、颈部血管B型超声检查,以及采取血液标本行有关生化指标检测,所有结果均输入专有数据库。结果共有2276例居民参加了调查,颈动脉病变流行率是53.8%,以单纯硬化和混合性病变为主,并且男性高于女性(64.03%vs 48.96%,P=0.0003),嗜酒、吸烟、少做家务及焦虑抑郁在有颈动脉病变的人群中流行率高于无颈动脉病变的人群,对颈动脉病变与物质代谢紊乱每个指标如高血压、糖尿病、高血脂、高尿酸血症、高同型半胱氨酸血症、C反应蛋白之间关系均非常密切。结论广州社区居民颈动脉病变的流行率高,加强对居民的正确生活习惯的宣传教育,以及动态监测病变对降低脑卒中发生风险非常必要。Objective To investigate the prevalence and risk factors of carotid artery disease in Guangzhou community residents. Methods From October 2018 to December 2019, the risk factors of cerebrovascular disease were investigated in 35 communities of Guangzhou. The contents included face-to-face questionnaire, on-site physical examination, sleep psychological test, and electrocardiogram, abdominal, gynecological and cervical vessel ultrasound examinations.Blood samples were used to test the biochemical indexes. Results A total of 2,276 residents were enrolled in this survey. The prevalence of carotid lesions was 53.8%, with simple sclerosis and mixed lesions predominating. The prevalence was significantly higher in men than in women(64.03% vs. 48.96%, P=0.000 3). The prevalence of alcoholism, smoking, less housework and anxiety or depression was significantly higher in population with carotid artery lesions than that in those without carotid artery lesions. Conclusions The prevalence of carotid artery disease in Guangzhou area is high. It is necessary to strengthen the propaganda and education of residents′ correct living habits and to dynamically monitor the disease to reduce the risk of stroke.

关 键 词：颈动脉病变 广州居民 流行率 脑卒中 相关因素 

分 类 号：R743.1[医药卫生—神经病学与精神病学] R195.4[医药卫生—临床医学]