颅内多发动脉瘤形成的相关危险因素分析  

Analysis of related risk factors for the formation of multiple intracranial aneurysms

作　　者：陈泽鑫[1] CHEN Zexin(The People's Hospital of Jieyang,Jieyang,Guangdong 522095,China)

机构地区：[1]揭阳市人民医院,广东省揭阳市522095

出　　处：《新疆医学》2021年第1期39-41,共3页Xinjiang Medical Journal

基　　金：揭阳市医学科学技术研究项目(项目编号:20190305)。

摘　　要：目的探讨颅内多发动脉瘤(MIA)形成的相关危险因素。方法回顾性分析2015年5月-2020年8月于揭阳市人民医院神经外科住院治疗的颅内动脉瘤患者326例,其中MIA患者58例纳入观察组,单发性动脉瘤268例纳入对照组。统计两组患者的性别、年龄、生活习惯如吸烟、饮酒及既往疾病史等临床资料,分析颅内多发动脉瘤形成危险因素。结果两组患者性别、吸烟、高血压、围绝经期等单因素比较,差异有统计学意义(P <0.05);年龄、饮酒、糖尿病、高尿酸血症、高胆固醇血症、高同型半胱氨酸血症等单因素比较,差异无统计学意义(P> 0.05)。Logistic回归分析显示,吸烟、围绝经期是颅内多发动脉瘤形成的独立危险因素(P <0.05且OR≥1)。结论吸烟、围绝经期是MIA形成的独立危险因素,临床应加强对该类患者的关注,并采取针对性干预措施,以改善患者预后。Objective To explore the risk factors associated with the formation of multiple intracranial aneurysms(MIA). Methods A retrospective analysis of 326 patients with intracranial aneurysms hospitalized in the people’s hospital of Jieyang of neurosurgery from May 2015 to March 2019 was performed. Among them, 58 MIA patients were included in the observation group and 268 single aneurysms were included in the control group. The clinical data of the two groups of patients including gender, age, lifestyle habits such as smoking,drinking, and previous disease history were analyzed, and the risk factors for the formation of multiple intracranial aneurysms were analyzed. Results The gender, smoking, hypertension, perimenopause and other single factors of the two groups were statistically significant(P < 0.05);age, drinking, diabetes, hyperuricemia, hypercholesterolemia, and hyperhomocysteinemia Compared with single factors such as alanine, the difference was not statistically significant(P > 0.05). Logistic regression analysis showed that smoking and perimenopause were independent risk factors for the formation of multiple intracranial aneurysms(P < 0.05 and OR≥1). Conclusions Smoking and perimenopause are independent risk factors for the formation of MIA. Clinical attention should be paid to these patients and targeted interventions should be taken to improve the prognosis of patients.

关 键 词：颅内多发动脉瘤形成 危险因素 吸烟 围绝经期 

分 类 号：R739.41[医药卫生—肿瘤]