草酸艾司西酞普兰联合心理护理对老年脑卒中合并抑郁患者的治疗效果  

Effect of escitalopram oxalate combined with psychological nursing on the treatment of elderly patients with stroke and depression

作　　者：李润霞 张峥 刘艳清 张欣[4] LI Runxia;ZHANG Zheng;LIU Yanqing;ZHANG Xin(Department of Psychiatry,Zhangjiakou Shalingzi Hospital,Zhangjiakou 075131,Hebei,China;Functional Division,Zhangjiakou Shalingzi Hospital,Zhangjiakou 075131,Hebei,China;Department of Internal Medicine,Zhangjiakou Kangbao County People's Hospital,Zhangjiakou 076650,Hebei,China;Department of Geriatrics,the Sixth People's Hospital of Hebei Province,Baoding 071000,Hebei,China)

机构地区：[1]张家口市沙岭子医院精神科,河北张家口075131 [2]张家口市沙岭子医院功能科,河北张家口075131 [3]康保县人民医院内科,河北张家口076650 [4]河北省第六人民医院老年科,河北保定071000

出　　处：《贵州医科大学学报》2021年第2期215-219,共5页Journal of Guizhou Medical University

基　　金：河北省医学科学研究重点课题计划项目(ZD201400461);张家口市科技计划项目(1821098D)。

摘　　要：目的探讨研究草酸艾司西酞普兰(百适可)联合心理护理治疗老年脑卒中并抑郁患者的效果。方法选取确诊的老年脑中风并抑郁患者80例,随机均分为对照组(百适可治疗)和观察组(百适可联合心理护理治疗),连续治疗3个月,比较治疗前后2组患者的临床表现评价临床疗效,采用汉密尔顿抑郁量表(HAMD)、美国国立卫生研究院卒中量表(NIHSS)、Barthel指数评定量表(BI)及简易智力状况检查法(MMSE)分别评估治疗前后2组患者的抑郁情况、神经功能缺损度、日常生活能力及认知功能,并观察2组患者治疗期间药物不良反应。结果治疗后观察组患者总有效率高于对照组,差异有统计学意义(P<0.05);2组患者治疗后HAMD和NIHSS评分均低于治疗前,且观察组患者治疗后HAMD和NIHSS评分均低于对照组(P<0.05);2组患者治疗后的BI评分和MMSE评分均高于治疗前,且观察组治疗后的BI评分、MMSE评分高于对照组,差异均有统计学意义(P<0.05);2组患者药物不良反应比较,差异无统计学意义(χ^2=0.74,P=0.39)。结论百适可联合心理护理干预对治疗老年脑卒中并抑郁患者有效,能改善抑郁情绪,促进神经功能的恢复,改善患者的生活质量。Objective To investigate the effect of escitalopram oxalate( baishike) combined with psychological nursing in the treatment of elderly patients with stroke and depression. Methods A total of 80 diagnosed elderly patients with stroke and depression were randomly divided into the control group( bashike treatment) and the observation group( bashike combined with psychological nursing treatment). The treatment lasted for 3 months. The clinical efficacy was evaluated based on the clinical manifestations of the patients before and after the treatment. Hamilton Depression Rating Scale( HAMD),the National Institutes of Health Stroke Scale( NIHSS),Barthel Index( BI) and Simple Intelligent Mental State Examination Scale( MMSE) before and after treatment were used to assess the depression,neurological deficit, ability of daily living, and cognitive function of the patients.Additionally,adverse drug reactions during the treatment were observed. Results After treatment,the total treatment efficiency of patients in the observation group was higher than that of patients in control group( P < 0. 05). The treatment lowered the HAMD and NIHSS scores. Both HAMD and NIHSS scores after treatment were less in the observation group than control group( P < 0. 05). The treatment raised the BI scores and MMSE scores, and the BI scores and MMSE scores of the observation group after treatment were higher than those of the control group( P < 0. 05). There was no significant difference in adverse drug reactions between the two groups( χ^2= 0. 74,P = 0. 39).Conclusion Bashike combined with psychological nursing is effective in the treatment of elderly patients with stroke and depression. It can attenuate depression,promote the recovery of neurological function,and improve the quality of life of patients.

关 键 词：抑郁 草酸艾司西酞普兰 心理治疗 老年脑卒中 神经功能 Barthel指数评分 

分 类 号：R749.05[医药卫生—神经病学与精神病学]