阿尔茨海默病^18F-AV45 PET脑显像的操作技术和临床应用  

Operation technology and clinical application of ^18F-AV45 PET imaging in Alzheimer's disease

作　　者：韩璎[1] 管一晖 郭起浩 任树华 谢芳 Han Ying;Guan Yihui;Guo Qihao;Ren Shuhua;Xie Fang(Department of Neurology,Xuanwu Hospital,Capital Medical University,Beijing 100053,China;PET Center,Huashan Hospital,Fudan University,Shanghai 200235,China;Department of Geriatrics,Sixth People's Hospital Affiliated to Shanghai Jiaotong University,Shanghai 200233,China)

机构地区：[1]首都医科大学宣武医院神经内科,北京100053 [2]复旦大学附属华山医院PET中心,上海200235 [3]上海交通大学附属第六人民医院老年病科,上海200233

出　　处：《中华神经医学杂志》2021年第1期2-7,共6页Chinese Journal of Neuromedicine

基　　金：国家重点研发项目(2016YFC1306305);国家自然科学基金(61633018、81801752);上海市临床重点专科一展两翼(shslczdzk03402);上海市青年科技英才扬帆计划(18YF1403200)。

摘　　要：^18F-florbetapir(AV45)正电子发射断层成像(PET)脑显像作为阿尔茨海默病早期诊断的一类无创性影像学手段,目前在国内已经逐渐被认可。规范的检查流程、检查技术、图像解读及报告书写将有助于获得高质量的图像和准确的定量分析数据。因此,在参考国内外相关指南并结合国内现状及实际操作经验的基础上,我们介绍了^18F-AV45 PET脑显像的操作技术和临床应用的相关内容,以更好地促进国内^18F-AV45 PET脑显像检查的规范开展和临床应用研究的推广,为患者提供准确的影像诊断服务。^18F-florbetapir(AV45)positron emission tomography(PET)imaging,as a non-invasive method for early diagnosis of Alzheimer's disease,has been gradually recognized in China.Standard examination procedures,standard examination techniques,and standard image interpretation and reports will help us to obtain high-quality images and accurate quantitative analysis data.Therefore,in reference to the domestic and foreign guidelines,the standardization examinations and clinical researches of^18F-AV45 PET in China are introduced based on the the current status of our country and clinical practical experience to provide accurate diagnosis services to the patients.

关 键 词：阿尔茨海默病 Β淀粉样蛋白 正电子发射断层成像 ^18F-florbetapir 

分 类 号：R749.16[医药卫生—神经病学与精神病学] R817.4[医药卫生—临床医学]