中西医结合治疗乙型肝炎病毒相关慢加急性肝衰竭患者对病死率的影响  

Effect of integrated traditional Chinese and western medicine on mortality of patients with hepatitis B virus related acute on chronic liver failure

作　　者：杨伟荣[1] 凌慧琪 刘仙梅 YANG Weirong;LING Huiqi;LIU Xianmei(the Second People's Hospital of Qinzhou,Qinzhou 535000,China)

机构地区：[1]钦州市第二人民医院,广西钦州535000

出　　处：《临床医学研究与实践》2021年第4期124-126,共3页Clinical Research and Practice

摘　　要：目的观察中西医结合治疗乙型肝炎病毒相关慢加急性肝衰竭患者对病死率的影响。方法将我院2017年1月至2020年5月收治的乙型肝炎病毒相关慢加急性肝衰竭患者60例根据入院顺序分成对照组(先入院的30例患者)和试验组(后入院的30例患者),每组30例。对照组采取常规西医综合治疗,试验组在对照组基础上配合中医治疗。比较两组临床疗效、肝功能指标及治疗不同时间段病死率。结果试验组治疗总有效率为73.33%,高于对照组的46.67%,差异具有统计学意义(P<0.05)。治疗后,两组肝功能指标水平均较治疗前下降,且试验组明显低于对照组(P<0.05)。试验组总病死率为3.33%,低于对照组的23.33%,差异具有统计学意义(P<0.05)。结论中西医结合治疗乙型肝炎病毒相关慢加急性肝衰竭患者,可明显提高临床治疗效果,降低患者病死率,效果理想。Objective To observe the effect of integrated traditional Chinese and western medicine on the mortality of patients with hepatitis B virus related acute on chronic liver failure.Methods A total of 60 patients with hepatitis B virus related acute on chronic liver failure admitted in our hospital from January 2017 to May 2020 were divided into control group(30 patients admitted first)and experimental group(30 patients admitted later)according to the order of admission,with 30 cases in each group.The control group was treated with conventional western comprehensive medicine,while the experimental group was treated with traditional Chinese medicine on the basis of the control group.The clinical efficacy,liver function indexes and mortality in different periods of treatment were compared between the two groups.Results The total effective rate of treatment in the experimental group was 73.33%,which was higher than 46.67%of the control group,and the difference was statistically significant(P<0.05).After treatment,the levels of liver function indexes in the two groups were lower than those before treatment,and those of the experimental group were significantly lower than the control group(P<0.05).The total mortality of the experimental group was 3.33%,which was lower than 23.33%of the control group,and the difference was statistically significant(P<0.05).Conclusion Integrated traditional Chinese and western medicine in the treatment of patients with hepatitis B virus related acute on chronic liver failure can significantly improve the clinical treatment effect,reduce the mortality of patients,with a ideal effect.

关 键 词：中西医结合治疗 乙型肝炎病毒 慢加急性肝衰竭 病死率 

分 类 号：R575.05[医药卫生—消化系统]