恶性肿瘤患者相关情绪障碍研究进展  

Research progress on emotional disorders in patients with malignant tumors

作　　者：林表君 张还珠[1] LIN Biao-jun;ZHANG Huan-zhu(Department of Oncology,First Affiliated Hospital of Guangzhou Medical University,Guangzhou 510230,P.R.China)

机构地区：[1]广州医科大学附属第一医院肿瘤内科,广州510230

出　　处：《中华肿瘤防治杂志》2020年第24期2006-2012,共7页Chinese Journal of Cancer Prevention and Treatment

摘　　要：目的随着恶性肿瘤发生率的升高,有关恶性肿瘤患者情绪障碍的发生情况、常见症状、发病机制、影响因素、预后及治疗等越来越受到重视。本研究通过回顾文献对恶性肿瘤相关情绪障碍的研究进展作一综述。方法利用PubMed及CNKI数据库,以"cancer、malignancy、anxiety、depression、mentality和immune"为关键词,检索2006-2019年相关文献。纳入标椎:(1)恶性肿瘤情绪障碍发病情况研究;(2)肿瘤相关情绪障碍发病机制及影响因素研究;(3)肿瘤相关情绪异常临床治疗预后研究。排除标准:相关研究中纳入人群为既往存在精神类疾病或器质性疾病引起精神症状的恶性肿瘤患者。纳入符合条件的文献66篇。结果情绪障碍在恶性肿瘤患者中存在较高发生率,其中以焦虑及抑郁较为常见。这一类心理障碍的发生与患者年龄、性别、经济水平、文化程度、疲倦和癌痛等相关,且对于肿瘤患者治疗疗效、生存质量有一定程度的影响。治疗上主要包括药物治疗、心理干预及运动疗法。结论恶性肿瘤患者产生的情绪障碍严重影响患者生存质量,也影响肿瘤的进展、治疗、预后和康复。对肿瘤患者进行合理筛查、准确评估和积极治疗,以提高患者生存质量及疾病治愈率等是亟待解决的问题。OBJECTIVE With the increasing incidence of malignant tumors,emotional disorders in patients with malignant tumors has received more attention,particularly in the following aspects:common symptoms,pathogenic mechanisms,influencing factors,disease prognosis and treatment.In this paper,research progress on malignant tumor-related emotional disorders is reviewed and demonstrated.METHODS To search the papers published from 2006 to 2019 on PubMed and CNKI database with the search terms of"cancer/malignancy"and"anxiety/depression/mentality"or"immune".Inclusion criteria:(1)studies on incidence of emotional disorders in patients with malignant tumors;(2)pathogenic mechanisms and influencing factors of tumor-related emotional disorders;(3)treatment and prognosis of tumor-related emotional disorders.Exclusion criteria:The subjects included in the study were malignant tumor patients with psychotic symptoms caused by previous mental illness or organic disease.At last,66 papers that conformed to the above-mentioned criteria were selected.RESULTS Emotional disorder have a high incidence in patients with malignant tumors,among which anxiety and depression are relatively common.Onset of such emotional disorders is associated with age,gender,economic level,education level,fatigue and cancer pain,which may influence the treatment efficacy and quality of life of cancer patients.The treatment mainly includes drug therapy,psychological intervention and exercise therapy.CONCLUSIONS Emotional disorders in patients with malignant tumors seriously affect the quality of life as well as tumor progression,treatment,prognosis and recovery.Therefore,appropriate screening,accurate evaluation and active treatment are of key importance for the improvement of patients’quality of life and disease cure rate.

关 键 词：恶性肿瘤 焦虑 抑郁 免疫 研究进展 

分 类 号：R730.1[医药卫生—肿瘤]