肠道微生态与自发性细菌性腹膜炎的关系  

Association between intestinal microecology and spontaneous bacterial peritonitis

作　　者：刘玉[1] 张宇一[1] 邹颖[1] 袁伟[1] 郭红英[1] 梅雪[1] 王介非[1] 钱志平[1] LIU Yu;ZHANG Yuyi;ZOU Ying;YUAN Wei;GUO Hongying;MEI Xue;WANG Jiefei;QIAN Zhiping(Department of Severe Liver Disease,Shanghai Public Health Clinical Center,Shanghai 201508,China)

机构地区：[1]上海市公共卫生临床中心重症肝病科,上海201508

出　　处：《临床肝胆病杂志》2021年第2期425-428,共4页Journal of Clinical Hepatology

基　　金：国家“十二五”科技重大专项(2018ZX10725506-002);2018年院级科研课题(KY-GW-2018-23)。

摘　　要：自发性细菌性腹膜炎(SBP)是终末期肝病的常见严重并发症,肠道微生态与SBP的发生、发展及预后密切相关,细菌易位是SBP发病的关键机制。归纳了肝硬化患者的肠道微生态特征,简述了肠道菌群在SBP发生、进展中的作用机制,为临床调整肠道微生态改善SBP提供理论基础。Spontaneous bacterial peritonitis(SBP)is a common serious complication of end-stage liver disease.Intestinal microecology is closely associated with the development,progression,and prognosis of SBP,and bacterial translocation is the key pathogenesis of SBP.This article summarizes the intestinal microecology in patients with liver cirrhosis and briefly describes the mechanism of action of intestinal flora in the development and progression of SBP,thus providing a theoretical basis for the clinical regulation of intestinal microecology and treatment of SBP.

关 键 词：腹膜炎 肝硬化 胃肠道微生物组 感染 

分 类 号：R575.2[医药卫生—消化系统]