TCT+HPV联合检查在宫颈癌早期筛查中的应用价值探究  

Practical value of TCT+HPV combined examination in the early screening of cervical cancer

作　　者：张君 ZHANG Jun(Department of Obstetrics and Gynecology,Haicheng Orthopedic Hospital,Haicheng 114200,China)

机构地区：[1]辽宁省海城市正骨医院妇产科,114200

出　　处：《中国现代药物应用》2021年第4期53-55,共3页Chinese Journal of Modern Drug Application

摘　　要：目的探究液基薄层细胞检测(TCT)+人乳头瘤病毒(HPV)联合检查在宫颈癌早期筛查中的应用价值。方法10641例体检育龄妇女进行宫颈癌早期筛查,其中812例妇女病理学检查显示阳性,所有妇女均分别进行宫颈刮片检查、TCT检查、HPV检查、TCT+HPV联合检查。统计并比较不同检查方法的检出情况。结果812例病理学检查显示阳性的妇女中,宫颈刮片检查检出568例,检出率为70.0%;TCT检查检出657例,检出率为80.9%;HPV检查检出702例,检出率为86.5%;TCT+HPV联合检查检出763例,检出率为94.0%。TCT+HPV联合检查检出率高于宫颈刮片检查、TCT检查、HPV检查,HPV检查检出率高于宫颈刮片检查、TCT检查,TCT检查检出率高于宫颈刮片检查,差异均有统计学意义(P<0.05)。结论在临床妇科宫颈癌筛查中,采取TCT+HPV联合检查能够有效提升样本检测的筛查效率,为尽快确诊疾病提供生物学检测依据,为后续治疗提供准确定性,在临床中具有较高的应用推广价值。Objective To investigate the practical value of thinprep cytologic test(TCT)+human papillomavirus(HPV)combined examination in the early screening of cervical cancer.Methods Among 10641 women of childbearing age who received physical examination,812 women were positive by pathological examination.All women were examined by cervical smear,TCT,HPV and TCT+HPV respectively.The detection status of different inspection methods were compared.Results Among 812 cases of women with positive pathological examination,568 cases were detected by cervical smear examination,with a detection rate of 70.0%;657 cases were detected by TCT examination,with a detection rate of 80.9%;702 cases were detected by HPV examination,with a detection rate of 86.5%;763 cases were detected by TCT+HPV combined examination,with a detection rate of 94.0%.The detection rate of TCT+HPV combined examination was higher than that of cervical smear,TCT and HPV examination,the detection rate of HPV examination was higher than that of cervical smear and TCT examination,and the detection rate of TCT was higher than that of cervical smear.The difference was statistically significant(P<0.05).Conclusion In clinical screening of gynecological cervical cancer,TCT+HPV combined examination can effectively improve the screening efficiency of sample detection,provide biological detection basis for the diagnosis of diseases as soon as possible,and provide accurate qualitativeness for follow-up treatment,which has high clinical application and promotion value.

关 键 词：宫颈癌 筛查早期 液基薄层细胞检测 人乳头瘤病毒检查 宫颈刮片检查 

分 类 号：R737.33[医药卫生—肿瘤]