胃癌根治术后早期复发转移的影响因素分析  

Risk Factors of Early Recurrence and Metastasis of Gastric Cancer After Radical Operation

作　　者：陈玲[1] 林晶[2] 陈丽珠[2] 陈誉[2] 王晓杰[2] 郭增清[2] 余家密[2] 郑静娴[2] CHEN Ling;LIN Jing;CHEN Li-zhu;CHEN Yu;WANG Xiao-jie;GUO Zeng-qing;YU Jia-mi;ZHENG Jing-xian(Fujian Cancer Hospital&Fujian Medical University Cancer Hospital,Fuzhou 350014,China)

机构地区：[1]福建省肿瘤医院,福建医科大学附属肿瘤医院腹部肿瘤内科,福建福州350014 [2]福建省肿瘤医院,福建医科大学附寓肿瘤医院,350014

出　　处：《肿瘤学杂志》2020年第12期1052-1055,共4页Journal of Chinese Oncology

基　　金：福建省科技计划项目(2018Y2003);福建省自然科学基金(2018J01267);福建省科技创新联合资金项目(2017Y9077);福建省福建省卫生厅青年课题(2016-1-11)。

摘　　要：[目的]探讨胃癌根治术后早期复发转移的影响因素。[方法]回顾性分析232例胃癌根治术后复发转移患者的临床病理特征,分析患者术后早期复发转移的影响因素。[结果] 232例患者中位复发时间为术后17.3个月(95%CI:15.0~19.6),早期复发转移(复发转移时间≤24个月)153例(65.9%),晚期复发转移(复发转移时间>24个月)79例(34.1%)。多因素分析显示神经侵犯(P=0.009)、术后并发症(P=0.013)是根治术后早期复发转移的独立危险因素。[结论]神经侵犯、术后并发症与胃癌根治术后早期复发转移相关。[Objective]To investigate the risk factors of early recurrence and metastasis of gastric cancer after radical operation.[Methods]The clinical data of 232 cases with early recurrence and metastasis of gastric cancer after radical operation were retrospective analyzed. The influencing factors of early recurrence and metastasis of gastric cancer after radical operation were analyzed.[Results]The mean recurrent time in 232 patients was 17.3 months after operation(95%CI:15.0~19.6). Among them,153 cases(65.9%) had early recurrence and metastasis(≤24 months),and 79 cases(34.1%) had late recurrence and metastasis(>24 months). Multivariate analysis showed that nerve infiltration(P=0.009) and postoperative complications(P=0.013) were independent risk factors for early recurrence and metastasis after radical operation.[Conclusion] Nerve infiltration and postoperative complications are related to early recurrence and metastasis in gastric cancer patients after radical gastrectomy.

关 键 词：胃肿瘤 胃切除术 复发转移 

分 类 号：R735.2[医药卫生—肿瘤]