Nuclear sphingomyelin in neurodegenerative diseases  

作　　者：Elisabetta Albi Alice V.Alessenko 

机构地区：[1]Department of Pharmaceutical Science,University of Perugia,Perugia,Italy [2]Emanuel Institute of Biochemical Physics,Russian Academy of Sciences,Moscow,Russia

出　　处：《Neural Regeneration Research》2021年第10期2028-2029,共2页中国神经再生研究（英文版）

摘　　要：Introduction:Recently,sphingolipids(SphLs)have become increasingly appreciated as a family of molecules involved in the growth,differentiation,and death of the central nervous system cells.The disequilibrium among the different SphLs leads to changes in the neuronal cell physiology and induces the development of neurodegenerative diseases(Alessenko and Albi,2020).Sphingomyelin(SM),sphinganin(Sphn),sphingosine(Sph),sphingosine-1-phosphate(S1P)and ceramide(Cer)are the most well-studied group of SphLs responsible for neurodegeneration,as well as derived molecules such as glucosylceramide or cerebroside(GCer)and galactosylceramide(GalCer)and finally more complex molecules such as as gangliosides.

关 键 词：finally SYSTEM SINE 

分 类 号：R741[医药卫生—神经病学与精神病学]