Do medullary thyroid carcinoma patients with high calcitonin require bilateral neck lymph node clearance?A case report  

作　　者：Feng-Jiao Gan Tie Zhou Shun Wu Meng-Xi Xu Su-Hong Sun 

机构地区：[1]Department of Thyroid and Breast Surgery,Affiliated Hospital of Zunyi Medical University,Zunyi 563000,Guizhou Province,China

出　　处：《World Journal of Clinical Cases》2021年第6期1343-1352,共10页世界临床病例杂志

基　　金：Supported by National Natural Science Foundation of China,No.81860469;Zunyi Science and Technology Bureau,China,ZunShi KeHe HZ(2019)No.85;Honghuagang District Science and Technology Bureau of Zunyi City,China,ZunHong KeHe Shezi(2018)No.12.

摘　　要：BACKGROUND In clinical work,85%-90%of malignant thyroid diseases are papillary thyroid cancer(PTC);thus,clinicians neglect other types of thyroid cancer,such as medullary thyroid carcinoma(MTC).CASE SUMMARY We report a 53-year-old female patient with a preoperative calcitonin level of 345 pg/mL.There was no definitive diagnosis of MTC by preoperative fine-needle aspiration cytology or intraoperative frozen pathology,but the presence of PTC and MTC was confirmed by postoperative paraffin pathology.The patient underwent total thyroidectomy and bilateral central lymph node dissection.Close follow-up at 1.5 years after surgery revealed no signs of recurrence or metastasis.CONCLUSION The issue in clinical work-up regarding types of thyroid cancer provides a novel and challenging idea for the surgical treatment of MTC.In the absence of central lymph node metastasis,it is worth addressing whether patients with high calcitonin can undergo total thyroidectomy and bilateral central lymph node dissection without bilateral lateral neck lymph node dissection.

关 键 词：Medullary thyroid carcinoma Papillary thyroid carcinoma Simultaneous different types of thyroid cancer CALCITONIN Fine needle aspiration cytology SURGERY Case report 

分 类 号：R736.1[医药卫生—肿瘤]