子宫肌壁间副中肾管囊肿临床病理诊断  

Clinicopathologic diagnosis of intramural paramesonephric cyst of uterus

作　　者：袁明明 任晓燕[1] 陶玉梅[1] 章小霞 顾丽丽 陈婷婷 YUAN Ming-ming;REN Xiao-yan;TAO Yu-mei;ZHANG Xiao-xia;GU Li-li;CHEN Ting-ting(Department of Pathology,Nantong Maternity and Child Care Hospital,Nantong 226006,China)

机构地区：[1]南通市妇幼保健院病理科,江苏南通226006

出　　处：《诊断病理学杂志》2020年第12期894-898,共5页Chinese Journal of Diagnostic Pathology

基　　金：南通市市级科技计划项目(MSZ18257)。

摘　　要：目的探讨子宫肌壁间副中肾管囊肿的临床病理特征。方法报道1例子宫肌壁间副中肾管囊肿患者的临床资料,观察其组织学形态、免疫表型,并复习相关文献。结果患者青年女性,体检发现子宫占位1个月余入院。临床诊断:子宫囊肿。行囊肿剥除术。组织学检查见囊肿内衬单层立方或柱状上皮,部分区域形成乳头状结构。上皮细胞胞质红染,核呈圆形或卵圆形,部分上皮表面可见纤毛。上皮下为平滑肌,未见子宫内膜间质。免疫组化示内衬上皮细胞CK_(pan)、CK7、CK18、ER、PR、WT1(+)。结论子宫肌壁间副中肾管囊肿罕见,易漏诊、误诊,需与中肾管囊肿及继发性囊肿等鉴别。Objective To explore the clinicopathological features,diagnosis and differential diagnosis of intramural paramesonephric cyst in the uterus.Methods One case of intramural paramesonephric cyst of uterus was studied by clinical data analyses,histopathologic observation and immunohistochemiscal staining.Results A young female patient presented with a pelvic cystic mass and the preoperative diagnosis was uterine cyst.A cystectomy was performed.Histologically,the wall of the lesion was composed of a layer of ciliated cuboidal epithelium that lineed the cyst,stromal cells,and smooth muscle.Immunohistochemically,the epithelial cells were positive for CK_(pan),CK7,CK18,ER,PR and WT1.Conclusions Intramural paramesonephric cyst of uterus is very rare and has a high misdiagnosis rate,and therefore it should be differentiated from mesonephric cysts and secondary cysts.

关 键 词：副中肾管囊肿 免疫组化 鉴别诊断 

分 类 号：R737.33[医药卫生—肿瘤]