Palladium-catalyzed oxidative homocoupling of 2-arylquinazolinones  

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作  者:Yadong Feng Zhengping Wu Ting Chen Qi Fu Qihua You Jinhai Shen Xiuling Cui 

机构地区:[1]College of Einviranment and Public Health,Xiamen Huaxia University,Xiamen 361024,China [2]Research Center of Molecular Medicime,Mdinistry of Education,Key Laboratory of Fujian Molecular Medicine,Key laboratory of Precision Medicine and Molecular Dinghosis of Fujian Universities,Key Laboratory of Xiamen Marine and Cene Drugs,School of Bionedical Sciencs,Huaqiao University Xiamen 361021,China

出  处:《Chinese Chemical Letters》2020年第12期3263-3266,共4页中国化学快报(英文版)

基  金:the National Natural Science Foundation of China(No.21572072);111 Project(No.BC2018061)and Y.Feng thanks the financial support of Scientific Research Foundation of Xiamen Huaxia University(No.HX201807);Outstanding Youth Scientific Research Cultivation Plan in Fujian Province University(No.201808);the Fujian Education and Scientific Research Project for Young and Middle-aged Teachers(No.JAT190990)。

摘  要:Pd-catalyzed oxidative homocoupling of 2-arylquinazolinones was successfully developed for the direct construction of biaryls via C—H bond activation.New well-defined structure that possessed two quinazolinone units was obtained with high efficiency and atomic economy.The protocols offer an efficient approach to the synthetically useful and functionalized biaryls in good yields using quinazolinone as a directing group.

关 键 词:2-Arylquinazolinones HOMOCOUPLING PALLADIUM-CATALYZED C—H bond activation 

分 类 号:O621.251[理学—有机化学]

 

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