Drosophila Ortholog of Mammalian Immediate-Early Gene Npas4 is Specifically Responsive to Reversal Learning  

作　　者：Tingting Liu Linghan Wang Qian Li 

机构地区：[1]School of Life Sciences,Tsinghua University,Beijing 100084,China

出　　处：《Neuroscience Bulletin》2021年第1期99-102,共4页神经科学通报（英文版）

基　　金：supported by grants from the National Natural Science Foundation of China (31970955 and 31700912)。

摘　　要：Dear Editor,In dynamic environments,the memory system of the brain must be able to perceive and process conflicting experiences to reach an adaptive decision.In Drosophila,in contrast to consistent experiences,conflicting experiences trigger significantly increased Rac1 activity which mediates active forgetting [1].The ability to cope with conflicting experiences but not simple learning experiences is impaired in mutants of multiple autism-risk genes [2].

关 键 词：Drosophila Ortholog of Mammalian Immediate-Early Gene Npas4 is Specifically Responsive to Reversal Learning 

分 类 号：R749.94[医药卫生—神经病学与精神病学]