超声介入治疗卵巢囊肿的临床效果分析  

Analysis of the clinical effect of ultrasound intervention in the treatment of ovarian cyst

作　　者：宋国超 卢峰[2] 赵建军 杨凯峰 孙英 Song Guochao;Lu Feng;Zhao Jianjun;Yang Kaifeng;Sun Ying(Department of ultrasound,Chongming branch,the Tenth People's Hospital Affiliated to Tongji University,Shanghai 202157;Department of ultrasound medicine,the Tenth People's Hospital Affiliated to Tongji University,Shanghai 200072;Department of ultrasound,the third people's Hospital of Chongming District,Shanghai,202153)

机构地区：[1]同济大学附属第十人民医院崇明分院超声科,上海市202157 [2]同济大学附属第十人民医院超声医学科,上海市200072 [3]上海市崇明区第三人民医院超声科,上海市202153

出　　处：《现代科学仪器》2021年第1期103-109,共7页Modern Scientific Instruments

摘　　要：目的探讨超声介入治疗卵巢囊肿的效果及对血清疼痛介质、糖类抗原199(CA199)、CA125水平的影响。方法选取2018年2月至2019年8月我院98例卵巢囊肿患者,按随机数字表法分为超声介入组(n=49)、开腹组(n=49)。超声介入组采取超声引导下介入手术,开腹组采取开腹囊肿切除术。比较2组手术情况、疗效、并发症与术前、术后12、24 h血清疼痛介质[P物质(SP)、5羟色胺(5-HT)]、术前、术后3个月、6个月血清CA199、CA125、卵巢功能指标[雌二醇(E2)、黄体生成素(LH)、卵泡刺激素(FSH)]水平。结果超声介入组手术时间、住院时间短于开腹组,术中出血量低于开腹组(P<0.05);超声介入组总有效率高于开腹组(P<0.05);超声介入组术后并发症发生率低于开腹组(P<0.05);超声介入组术后12、24 h血清SP、5-HT水平低于开腹组(P<0.05);超声介入组术后3个月、6个月血清CA199、CA125水平低于开腹组(P<0.05);超声介入组术后3个月、6个月血清E2、LH、FSH水平低于开腹组(P<0.05)。结论超声介入治疗卵巢囊肿患者,具有创伤小、手术时间短、出血少、并发症少、恢复快等优势,可降低血清疼痛介质、CA199、CA125水平,减轻对卵巢功能的影响,效果显著。Objective To investigate the effect of ultrasound interventional therapy on ovarian cysts and its effect on serum pain mediators,carbohydrate antigen 199(CA199)and CA125 levels.Methods 98 patients with ovarian cysts in our hospital from February 2018 to August 2019 were selected and divided into an ultrasound intervention group(n=49)and an laparotomy group(n=49)according to the random number table method.Ultrasound guided interventional surgery was performed in the ultrasound intervention group,and open cyst resection was performed in the laparotomy group.The operation conditions,efficacy,complications and serum pain mediators[substance P(SP),serotonin(5-HT)]before and after operation at 12 and 24 hours,serum CA199,CA125,ovarian function indexes[estradiol(E2),luteinizing hormone(LH),follicle stimulating hormone(FSH)]levels before operation,3 months and 6 months after operation of the two groups were compared.Results The operation time and hospital stay in the ultrasound intervention group were shorter than those in the laparotomy group,and the intraoperative blood loss was lower than that in the laparotomy group(P<0.05);the total effective rate of the ultrasound intervention group was higher than that of the laparotomy group(P<0.05);the incidence of postoperative complications in the ultrasound intervention group was lower than that of the laparotomy group(P<0.05);the levels of serum SP and 5-HT in the ultrasound intervention group were lower than those in the laparotomy group at 12 and 24 hours after operation(P<0.05);the levels of serum CA199 and CA125 in the ultrasound intervention group were lower than that in the laparotomy group at 3 and 6 months after operation(P<0.05);the level of serum E2,LH and FSH in the ultrasound intervention group was lower than that in the laparotomy group at 3 and 6 months after operation(P<0.05).Conclusion Ultrasound interventional therapy for patients with ovarian cysts has the advantages of less trauma,shorter operation time,less bleeding,less complications,and faster recovery.

关 键 词：卵巢囊肿 超声介入 临床效果 

分 类 号：R73[医药卫生—肿瘤]