输尿管镜下肿瘤切除术治疗上尿路肿瘤的临床效果  

Clinical effect of ureteroscopic tumor resection in the treatment of upper urinary tract tumor

作　　者：雷茹茹 张晓林 刘力婕[1] 陈怀安[1] LEI Ruru;ZHANG Xiaolin;LIU Lijie;CHEN Huai’an(Department of Urology,the First Affiliated Hospital of Hebei North University,Hebei Province,Zhangjiakou 075000,China)

机构地区：[1]河北北方学院附属第一医院泌尿外科,河北张家口075000

出　　处：《中国医药导报》2021年第3期67-70,共4页China Medical Herald

基　　金：河北省医学科学研究重点课题计划项目(2020056)。

摘　　要：目的研究输尿管镜下肿瘤切除术治疗上尿路肿瘤的临床效果。方法选取2014年4月—2016年4月河北北方学院附属第一医院收治的96例上尿路肿瘤患者,按随机数字表法分为两组,各48例。对照组患者给予传统开放手术治疗,观察组患者给予输尿管镜下肿瘤切除术治疗。观察两组手术情况、生活质量、疼痛情况以及并发症情况。随访1、2、3年观察患者生存情况。结果观察组手术时间、肛门首次排气时间、拔管时间及住院时间均短于对照组,出血量少于对照组,差异有统计学意义(P<0.05)。术后,两组ADL评分高于术前,VAS低于术前,且观察组ADL评分高于对照组,VAS低于对照组,差异有统计学意义(P<0.05)。观察组并发症发生率低于对照组,差异有统计学意义(P<0.05)。两组随访1、2、3年生存率比较,差异无统计学意义(P>0.05)。结论输尿管镜下肿瘤切除术治疗上尿路肿瘤与开放式手术治疗的效果相近,但配合良好的术后护理,能明显改善患者生活质量,缓解疼痛,缩短恢复时间,安全性较高。Objective To study clinical effect of ureteroscopic tumor resection in the treatment of upper urinary tract tumor.Methods Ninety-six patients with upper urinary tract tumor admitted to the First Affiliated Hospital of Hebei North University from April 2014 to April 2016 were included and divided into two groups according to the random number table,48 cases in each group.Control group were treated with traditional open surgery,and observation group were treated with ureteroscopic tumor resection.The operation,quality of life,pain and complications between two groups were observed.The patients were followed up for one,two,three years.Results The operation time,first anal exhaust time,extubation time and hospitalization time of observation group were shorter than those of control group,and the amount of bleeding of observation group was less than that of control group,the differences were statistically significant(P<0.05).After operation,ADL score of two groups was higher than that before operation,and VAS of two groups was lower than that before operation,ADL score of observation group was higher than that of control group,and VAS of observation group was lower than that of control group(P<0.05).The incidence rate of complication in observation group was lower than that in control group(P<0.05).There was no significant difference in one,two,three year survival rate between two groups(P>0.05).Conclusion The effect of ureteroscopic resection for upper urinary tract tumor is similar to that of open surgery,but with good postoperative care,it can significantly improve the quality of life,relieve pain,shorten the recovery time,and have high safety.

关 键 词：输尿管镜下肿瘤切除术 上尿路肿瘤 开放手术 护理效果 

分 类 号：R737.1[医药卫生—肿瘤]