抗生素耐药与肠道菌群的研究进展  

Research progress on antibiotic resistance and intestinal flora

作　　者：张义楠 袁文焕 兰力伟 刘红星 白忠良 杨福 王素英[1] 范寰[6] ZHANG Yi-nan;YUAN Wen-huan;LAN Li-wei;LIU Hong-xing;BAI Zhong-liang;YANG Fu;WANG Su-ying;FAN Huan(不详)

机构地区：[1]天津商业大学生物技术与食品科学学院天津市食品生物技术重点实验室,天津300134 [2]天津市武清区农业农村委员会,天津301700 [3]天津市宝坻区大口屯兽医站,天津301801 [4]天津市蓟州区畜牧业发展服务中心,天津301900 [5]天津市蓟州区动物卫生监督所,天津301900 [6]天津市农业科学院畜牧兽医研究所,天津300381

出　　处：《饲料研究》2021年第1期139-142,共4页Feed Research

基　　金：天津市武清区科技发展计划科技合作项目(项目编号:WQKJ201929)。

摘　　要：抗生素因具有促进生长、治疗细菌感染等作用广泛应用于养殖业中。但是,抗生素耐药菌和耐药基因大量出现并在肠道菌群中传播,给畜禽安全及人类健康带来风险。文章就抗生素对肠道免疫及代谢的影响、抗生素耐药基因产生与传播途径及抗生素对肠道菌群构成的影响进行综述,为抗生素替代品的研究提供参考。Antibiotics are widely used in aquaculture because of the functions of promoting growth and treating bacterial infection. However, a large number of antibiotic resistant bacteria and resistant genes appear and spread in the intestinal flora, which brings risks to the safety of livestock and human health. The paper reviews the effect of antibiotic use on intestinal immunity and metabolism, the generation and transmission of antibiotic resistance genes, and the effect of antibiotic on the composition of intestinal flora, then provides reference for the study of antibiotic replacement.

关 键 词：抗生素 免疫 代谢 抗生素耐药基因 肠道菌群 

分 类 号：S811.6[农业科学—畜牧学]