Hijack to escape:a geminivirus seizes a host imprinted E3 ligase to escape epigenetic repression  

作　　者：Xueping Zhou 

机构地区：[1]State Key Laboratory for Biology of Plant Diseases and Insect Pests,Institute of Plant Protection,Chinese Academy of Agricultural Sciences,Beijing 100193,China [2]State Key Laboratory of Rice Biology,Institute of Biotechnology,Zhejiang University,Hangzhou 310058,China

出　　处：《Science China(Life Sciences)》2021年第2期323-325,共3页中国科学（生命科学英文版）

基　　金：supported by grants from the National Natural Science Foundation of China(31720103914 and 31930089)。

摘　　要：Geminivirus infection triggers both transcriptional and posttranscriptional RNA silencing(RNA interference,RNAi)antiviral mechanisms.Much is known about the geminivirus-encoded viral suppressors of RNA silencing(VSRs)interfering with host RNAi machineries.However,how transcription of these VSRs escapes from epigenetic silencing remains unknown.Chen et al.(2020)provide compelling evidence for the epigenetic activation of VSRs via geminivirus-induced VIM5,a plant imprinted E3 ligase gene,leading to post-translational degradation of host DNA methyltransferases(Chen et al.,2020).

关 键 词：EPIGENETIC al. IMPRINT 

分 类 号：S432.41[农业科学—植物病理学]