依达拉奉对脑出血患者血清铁蛋白的影响  

The Influence of Edaravone on SF in Patients With Cerebral Hemorrhage

作　　者：林霞[1] LIN Xia(The First Department of Neurology,The First Hospital of Tianshui,Tianshui Gansu 741000,China)

机构地区：[1]天水市第一人民医院神经内一科,甘肃天水741000

出　　处：《中国继续医学教育》2021年第6期139-142,共4页China Continuing Medical Education

摘　　要：目的观察依达拉奉对脑出血(cerebral hemorrhage,CH)患者血清铁蛋白(serum ferritin,SF)、神经功能缺损评分(neurological deficit score,NIHSS)的作用。方法选取2018年1月—2019年10月就诊的CH患者90例,区组随机化分组分为依达拉奉治疗组,常规药物治疗组。CH入组患者于入院后第1 d,第7 d及第14 d,检测SF、评估NIHSS,详细记录并分别对比依达拉奉治疗组,常规药物治疗组CH患者的SF、NIHSS。结果依达拉奉治疗组,常规药物治疗组入院后第1 d的SF、NIHSS无差距(P>0.05)。依达拉奉治疗组相对于常规药物治疗组,其入院后第7 d,第14 d SF、NIHSS差距显著(P<0.05)。结论依达拉奉可通过改善CH患者的SF和NIHSS,减少CH后引起的脑部损伤,促进患者相关功能恢复。Objective To observe the effect of edaravone on serum ferritin(SF)and neurological deficit score(NIHSS)in patients with cerebral hemorrhage(CH).Methods 90 patients from January 2018 to October 2019 with CH were randomized block grouping into edaravone treatment group and routine treatment group.Patients with CH were enrolled in the study on the first day,the seventh day and the fourteenth day after admission.SF was detected and NIHSS was evaluated.Detailed record and comparison of edaravone treatment group,routine treatment group of patients with CH serum ferritin,neurological deficit score.Results There was no significant difference in SF and NIHSS between edaravone treatment group and routine treatment group on the first day after admission(P>0.05).Edaravone treatment group compared with routine treatment group,there were significant differences in SF and NIHSS between 7 d and 14 d after admission(P<0.05).Conclusion Edaravone can improve the SF and NIHSS of patients with CH,reduce the brain damage caused by CH,and promote the recovery of related functions of patients.

关 键 词：脑出血 依达拉奉 血清铁蛋白 神经功能缺损评分 铁超载 自由基清除剂 

分 类 号：R743[医药卫生—神经病学与精神病学]