广东省2015-2018年并指(趾)流行状况分析  

Prevalence of syndactyly in Guangdong Province from,2015-2018

作　　者：徐昊立 方俊[1] 王雄虎[1] 罗灿[1] 朱颖贤 刘风华[1] XU Hao Li;FANG Jun;WANG Xiong Hu;LUO Can;ZHU Ying Xian;LIU Feng Hua(Guangdong Women and Children Hospital,Guangzhou 511442,China)

机构地区：[1]广东省妇幼保健院,广州511442

出　　处：《中国妇幼卫生杂志》2021年第1期20-23,共4页Chinese Journal of Women and Children Health

基　　金：广东省医学科研基金(C2019065)。

摘　　要：目的了解2015-2018年广东省并指(趾)流行状况。方法以2015-2018年在广东省出生缺陷监测体系内57家医院分娩的围产儿(孕28周至出生后7天)及产妇为研究对象,描述性分析广东省并指(趾)分布及类型特征。结果符合标准的围产儿1147063例纳入围产儿的出生缺陷监测,符合并指(趾)分类标准者916例,检出率为7.99/万,其中并指、并趾、并指和趾的检出率分别为4.47/万、3.13/万、0.38/万;2015-2018年逐年检出率分别为7.62/万、6.51/万、7.82/万、9.93/万,年份间分布趋势经卡方趋势检验,差异有统计学意义(χ^(2)=12.12,P<0.001);并指(趾)检出率月份波动无明显的趋势性,并指(趾)月份分布差异无统计学意义(χ^(2)=2.08,P=0.15),单纯并指和并指(趾)在冬季检出率相对较高,其中12月份检出率最高。不同年龄组产妇的并指(趾)畸形的检出率差异无统计学意义(χ^(2)=2.21,P=0.69)。不同性别间并指(趾)的检出率差异有统计学意义(χ^(2)=14.33,P<0.01),总检出率男性/女性为1.29。结论进一步研究并指(趾)检出率升高的影响因素,普及优生优育及出生缺陷防控相关健康教育,以减少出生缺陷的发生。Objective To analyze the prevalence of syndactyly during 2015 and 2018 in Guangdong province.Method Perinatal infants(28 weeks of pregnancy to 7 days after birth)and pregnant women delivered in 57 hospitals in Monitoring System of Birth Defects in Guangdong Province from 2015 to 2018 were selected as subjects.Descriptive analysis was used to analyze the distribution and type characteristics of syndactyly in Guangdong Province.Result A total of 1,147,063 medical records were anaylzed and the birth prevalence of Syndactyly was 13.82/10,000 from 2015 to 2018.The rate of Syndactyly(fingers),Syndactyly(toes)and/10,000,0.38/10,000 and 9.93 differen years was tested by chi-square trend test,and the difference was statistically significant(χ^(2)=12.12,P<0.001).However,there was no statistically difference beween monthly incidences(χ^(2)=2.08,P=0.15).The detection rate of simple syndactyly and syndactyly(toe)was relatively high in winter,and the detection rate was the highest in December.There was no significant difference in the detection rate of syndactyly(toe)among different age groups(χ^(2)=2.21,P=0.69).There was significant difference in the detection rate of syndactyly(toe)between genders(χ^(2)=14.33,P<0.01).The ratio of male/female was 1.29.Conclusion It’s necessary to study the influencing factors of the increase in the detection rate of syndactyly(toe),to premote health education related to eugenics and birth defect prevention and control in order to reduce the occurrence of birth defects.

关 键 词：并指(趾) 出生缺陷 围产儿 

分 类 号：R726.8[医药卫生—儿科]