MicroRNA-125与缺血性脑卒中的相关性研究进展  

Research progress on the correlation between microRNA-125 and ischemic stroke

作　　者：刘湘雯 张卓伯[1] Liu Xiangwen;Zhang Zhuobo(Ward 3,Department of Neurology,the Fourth Hospital of Medical University,Harbin 150000,China)

机构地区：[1]哈尔滨医科大学附属第四医院神经内科三病房,150000

出　　处：《神经疾病与精神卫生》2020年第10期713-716,共4页Journal of Neuroscience and Mental Health

摘　　要：脑卒中以缺血性脑卒中为主,其发病率及复发率高,是致死、致残率日益增长的非传染性疾病。研究表明microRNA-125(miR-125)可参与缺血性脑卒中的多种病理生理过程,miR-125的表达与静脉溶栓、血管内溶栓的预后情况有显著的相关性。现就miR-125与缺血性脑卒中的相关性研究进展作一综述。Stroke is dominated by ischemic stroke,which has a high incidence and recurrence rate.It is a non-communicable disease with increasing mortality and disability rate.Studies have shown that microRNA-125(miR-125)can participate in various pathophysiological processes of ischemic stroke,and the expression of miR-125 is significantly correlated with the prognosis of intravenous and intravascular thrombolysis.This article summarizes the research progress of the correlation between miR-125 and ischemic stroke.

关 键 词：缺血性脑卒中 miR-125 炎症级联反应 综述 

分 类 号：R743.3[医药卫生—神经病学与精神病学]