磁共振成像评估舌鳞状细胞癌浸润深度的准确性分析  

Accuracy analysis of MRI in the depth of invasion assessment of tongue squamous cell carcinoma

作　　者：李明[1] 南欣荣[2] 原振英 唐瞻贵[1] LI Ming;NAN Xinrong;YUAN Zhenying;TANG Zhangui(Xiangya Stomatological Hospital,Central South University,Changsha 410000,China;Department of Stomatology,First Hospital of Shanxi Medical University,Taiyuan 030001,China)

机构地区：[1]中南大学湘雅口腔医院,湖南长沙410000 [2]山西医科大学第一医院口腔科,山西太原030001

出　　处：《口腔疾病防治》2021年第5期322-327,共6页Journal of Prevention and Treatment for Stomatological Diseases

基　　金：国家自然科学基金项目(8167041124)。

摘　　要：目的以光镜下病理切片为参照,分析磁共振成像(magnetic resonance imaging,MRI)测量的舌鳞状细胞癌浸润深度的准确性,为临床提供参考。方法选取2018年1月至2020年9月就诊于山西医科大学第一医院口腔科和中南大学湘雅口腔医院的73例舌鳞状细胞癌患者,术前均行MRI评估舌鳞状细胞癌浸润深度,术中冰冻病理切片再次测量舌鳞状细胞癌浸润深度。结果T1加权成像测量的舌鳞状细胞癌浸润深度较病理结果平均高估1.11 mm(95%CI=0.51~1.70,t=3.72,P<0.001),相关系数r为0.95;T2加权像平均高估2.17 mm(95%CI=1.32~3.02,t=5.10,P<0.001),相关系数r为0.92。Bland⁃Altman图显示T1、T2加权像与病理测量的浸润深度一致性佳。结论MRI测量的舌鳞状细胞癌浸润深度较为准确,与病理测量结果相比有平均1~2 mm的高估,其中T1加权像优于T2加权像。Objective To analyze the accuracy of the infiltrating depth of tongue squamous cell carcinoma measured by magnetic resonance imaging(MRI)using pathological sections under a light microscope to provide a clinical reference.Methods Seventy⁃three patients with tongue squamous cell carcinoma who visited the Department of Stomatology of the First Hospital of Shanxi Medical University and Xiangya Stomatological Hospital from January 2018 to September 2020 were selected.Preoperative MRI was performed to evaluate the infiltration depth of tongue squamous cell carcinoma,and intraoperative frozen pathological sections were used to confirm the infiltration depth of tongue squamous cell carcinoma measurement.Results The infiltration depth of tongue squamous cell carcinoma measured by T1⁃weighted imaging was 1.11 mm(95%CI=0.51-1.70;t=3.72;P<0.001),and the correlation coefficient r was 0.95.The T2⁃weighted average overestimation was 2.17 mm(95%CI=1.32⁃3.02;t=5.10;P<0.001),and the correlation coefficient was 0.92.The Bland⁃Altman plot showed good consistency between T1⁃and T2⁃weighted images and patho⁃logic measurements.Conclusion The infiltration depth of tongue squamous cell carcinoma measured by MRI is more accurate,with an average overestimation of 1-2 mm compared with pathological measurements,and T1⁃weighted images are better than T2⁃weighted images.

关 键 词：鳞状细胞癌 舌鳞状细胞癌 口腔鳞状细胞癌 口腔癌 舌肿瘤 浸润深度 磁共振成像 病理检查 

分 类 号：R78[医药卫生—口腔医学] R739.8[医药卫生—临床医学]