Three-dimensional structure of the antennal lobe in the Southern house mosquito Culex quinquefasciatus  

作　　者：Zi Ye Feng Liu Nannan Liu 

机构地区：[1]Department of Biological Sciences,Vanderbilt University,Nashville,Tennessee,USA [2]Department of Entomology and Plant Pathology,Auburn University,Auburn,Alabama,USA

出　　处：《Insect Science》2021年第1期93-102,共10页昆虫科学（英文版）

基　　金：an award from the Alabama Agricultural Experiment Station(AAES)Multistate/Hatch Grants ALA08-045,ALA015-1-10026,and ALA015-1-16009 to N.L.NL,ZY,and FL conceived and designed the study.ZY and FL performed the experiments.NL prepared the materials.NL,ZY,and FL wrote the main manuscript.All authors reviewed the manuscript.

摘　　要：The Southern house mosquito Culex quinquefasciatus relies on its olfactory system to locate the human hosts for blood meals,by which several deadly diseases are transmitted.Olfactory sensory neurons(OSNs)housed in the sensilla on the olfactory appendages send their axons into the antennal lobes(ALs),the primary olfactory center in the brain,where the OSNs expressing the same olfactory receptors converge upon the same spherical structures known as glomeruli in the AL.The structure of the antennal lobe,that is,the spatial organization of the glomeruli,governs the insect's odor identification and discrimination.Drosophila studies have demonstrated the specific connections between receptors and glomeruli based on the 3D structure of the antennal lobe,deepening our understanding of the relationships between glomerular activities and behaviors,but as yet the structure of the Cx.quinquefasciatus antennal lobe remains unknown.We therefore constructed a 3D model of the Cx.quinquefasciatus antennal lobe using nc82 antibody staining,identifying 62 and 44 glomeruli in the female and male mosquito antennal lobe,respectively,with a significant sexual dimorphism in terms of the antennal lobe volume and glomerulus number.These results demonstrate the structural basis of mosquito odor coding and provide a platform for future studies of the mosquito olfactory signal processing mechanism.

关 键 词：3D-reconstruction antennal lobe Culex quinquefasciatus GLOMERULUS OLFACTION 

分 类 号：Q96[生物学—昆虫学]