supported by the National Key Research and Development Program of China(No.2020YFA0803900);the National Natural Science Foundation of China(No.81872943)。
Prednisone is a synthetic glucocorticoid that is commonly used in both human and veterinary medication.Now,it is also recognized as an emerging environmental contaminant.Pregnantwomenmay be exposed to prednisone activ...
supported by the National Natural Science Foundation of China(32130089);the Norwegian Research Council(324379)。
In insects,the number and specificity of antennal lobe glomeruli often reflect the number and diversity of expressed chemosensory genes,which are linked to its ecological niche and specific olfactory needs.The orienta...
sponsored by Regional Demonstration Project of Marine Economic Innovation and Development in 2014 and 2016,the National Key Research and Development Program of China(2018YFD0901102);K.C.Wong Magna Fund of Ningbo University.
Diabetic nephropathy(DN)is a common type of end-stage renal disease and glomerular mesangial cells(GMCs)are widely used as a cell model for DN.This study firstly investigated the inhibitory effects of the Apostichopus...
Focal segmental glomerulosclerosis (FSGS) is characterized histologically by hyalinosis and sclerosis of glomeruli associated or not with podocyte involvement. The objective of our work was to clarify the epidemiologi...
This work was supported by the Regional Innovation and Development Joint Fund(No.U20A20411);the National Science Fund for Excellent Young Scholars(No.82022070).
The etiology of chronic kidney disease(CKD)is complex and diverse,which could be briefly categorized to glomerular-or tubularoriginated.However,the final outcomes of CKD are mainly glomerular sclerosis,endothelial dys...
The effective filtration area is determined by the length of capillaries in the glomerulus,however,a quantitative morphological data describing it is not available.Present study aims a quantitatively describing the de...
an award from the Alabama Agricultural Experiment Station(AAES)Multistate/Hatch Grants ALA08-045,ALA015-1-10026,and ALA015-1-16009 to N.L.NL,ZY,and FL conceived and designed the study.ZY and FL performed the experiments.NL prepared the materials.NL,ZY,and FL wrote the main manuscript.All authors reviewed the manuscript.
The Southern house mosquito Culex quinquefasciatus relies on its olfactory system to locate the human hosts for blood meals,by which several deadly diseases are transmitted.Olfactory sensory neurons(OSNs)housed in the...
the National Natural Science Foundation of China (Nos. 81473169 and 81130060).
Mesangial proliferative glomerulonephritis (MsPGN),one of the most common glomerulonephritis pathological types,often leads to end-stage renal disease over a prolonged period.But the current treatment of MsPGN is non-...
The reported work was supported in part by research grants from the National Institutes of Health(CA226303 to TCH);the National Key Research and Development Program of China(2016YFC1000803 and 2011CB707906 to TCH);This project was also supported in part by The University of Chicago Cancer Center Support Grant(P30CA014599);the National Center for Advancing Translational Sciences of the National Institutes of Health through Grant Number UL1 TR000430.
Glomerular podocytes are highly specialized epithelial cells and play an essential role in establishing the selective permeability of the glomerular filtration barrier of kidney.Maintaining the viability and structura...
Background: Chronic kidney disease has become a leading public health concern in China, as it is associated with increased morbidity, mortality, and costs. However, the overall situation regarding common glomerular d...