MESANGIAL

作品数:100被引量:88H指数:6
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相关领域:医药卫生更多>>
相关作者:赵姗姗姚源璋黄国东郑维耿晓东更多>>
相关机构:江苏省中西医结合医院南京中医药大学广西中医药大学中国人民解放军总医院更多>>
相关期刊:《Chinese Medical Journal》《外科研究与新技术(中英文)》《Acta Pharmacologica Sinica》《World Journal of Nephrology》更多>>
相关基金:国家自然科学基金更多>>
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Regulatory role of the mTOR signaling pathway in autophagy and mesangial proliferation in IgA nephropathy
《中南大学学报(医学版)》2024年第8期1220-1231,共12页LIU Yexin LENG Bin XIA Ming LIU Di TAN Xia CHEN Guochun HE Liyu WANG Chang ZHU Xuejing LIU Hong 
supported by the Key Funding Project of Hunan Provincial Health Commission(A202303057091);the Nephrology Medical Development Research Fund Project(20220316ZN),China.
Objective:IgA nephropathy(IgAN)is the most common primary glomerular disease in China,but its pathogenesis remains unclear.This study aims to explore the regulatory role of the mammalian target of rapamycin(mTOR)signa...
关键词:mammalian target of rapamycin AUTOPHAGY mesangial proliferation IgA nephropathy 
Lupus Nephritis Class II: A Challenging Entity
《Open Journal of Nephrology》2022年第2期203-213,共11页Basmat Amal Chouhani Ghita Elbardai Laila Tahiri Elousrouti Nadia Kabbali Hind Elfatemi Tarik Sqalli Houssaini 
Most of the literature focused on the proliferative forms of the lupic Glomerulonephritis. Clinicians are increasingly confronted with cases of lupic nephropathy purely mesangial (class II). The aim of our study is to...
关键词:Lupus Nephritis Mesangial Nephropathy RELAPSE 
A novel compound AB38b attenuates oxidative stress and ECM protein accumulation in kidneys of diabetic mice through modulation of Keap1/Nrf2 signaling被引量:14
《Acta Pharmacologica Sinica》2020年第3期358-372,共15页Lei Du Lei Wang Bo Wang Jin Wang Meng Hao Yi-bing Chen Xi-zhi Li Yuan Li Yan-fei Jiang Cheng-cheng Li Hao Yang Xiao-ke Gu Xiao-xing Yin Qian Lu 
The work was supported by the National Natural Science Foundation of China(No.81473257);the Qing Lan project,the Natural Science Foundation of Jiangsu Province(No.BK20151155);the“333”Foundation of Jiangsu Province(No.BRA2015329);the Key Natural Science Foundation of Jiangsu Higher Education Institutions of China(No.15KJA310005);the Jiangsu Overseas Research&Training Program for University Young&Middle-aged Teachers and Presidents,the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD);the Science and Technology Project of Xuzhou(No.KC18202).
Extracellular matrix(ECM)deposition following reactive oxygen species(ROS)overproduction has a key role in diabetic nephropathy(DN),thus,antioxidant therapy is considered as a promising strategy for treating DN.Here,w...
关键词:AB38b RESVERATROL antioxidant diabetic NEPHROPATHY oxidative stress ECM NRF2 Keapl glomerular MESANGIAL cells 
Analysis of the Clinical Effect of Laparoscopic Total Mesorectal Excision for the Treatment of Middle and Low Rectal Cancer
《Advances in Modern Oncology Research》2019年第6期10-14,共5页Ki Chang Keum Lisa Cooper 
The purpose of this study was to analyze the clinical efficacy of laparoscopic total mesorectal excision for the treatment of middle and low rectal cancer.First,30 patients who received treatment in the hospital from ...
关键词:LAPAROSCOPE Total mesangial rectal resection Middle and low rectal cancer 
Effectiveness of Qingre Lishi Yishen decoction on the glomerular fibrosis of immunoglobulin A nephropathy in a rat’s model被引量:2
《Journal of Traditional Chinese Medicine》2019年第4期516-523,共8页Dang Wanyu Hou Linyi Yan Huimin Wu Xiaoming Zhen Xiaofang Hao Jing 
Supported by Monographic Research of Capital Traditional Chinese Medicine(No.3500-11723360)
OBJECTIVE: To investigate the effect of the clinical effective prescription of Qingre Lishi Yishen decoction(QRLS) on the activation of mesangial cells in immunoglobulin A nephropathy(IgAN) rats.METHODS: IgAN rat’s m...
关键词:Glomerulonephritis IGA MESANGIAL cells FIBRONECTINS Tumor NECROSIS FACTOR-ALPHA Qingre Lishi Yishen DECOCTION 
Melatonin inhibits high glucose-induced cell proliferation and expressions of inflammatoryfactor via Toll-like receptor 4 signaling pathway inmouse mesangial cells
《China Medical Abstracts(Internal Medicine)》2019年第2期116-116,共1页REN Lili 
Objective To investigate effects of melatonin (MT)on high glucose-induced cell proliferation,Toll-like receptor4 ( TLR4) signaling pathway and expressions ofinflammatory factor in mouse mesangial cells ( SV40).Methods...
关键词:TAK MELATONIN INHIBITS high glucose-induced cell proliferation inflammatoryfactor via TOLL-LIKE receptor 4 signaling pathway inmouse MESANGIAL cells 
Jixuecao(Herba Centellae Asiaticae) alleviates mesangial cell proliferation in IgA nephropathy by inducing mitofusin 2 expression被引量:6
《Journal of Traditional Chinese Medicine》2019年第3期346-355,共10页Chen Hongyu Du Yuanyuan Li Yayu Zeng Jiali Miao Jianxia Jiang Xue 
Supported by Hangzhou Health Technology Project:Study of the Relationship Between Mitofusin 2 And Cyclosporine A Nephropathy(No.2018A52);National Natural Science Foundation of China:Study on Mechanism of Centella Asiatica Compound in the Treatment of Iga Nephropathy by Regulating Mesangial Cell Proliferation via Mitofusin 2(No.81373631)
OBJECTIVE:To investigate the effect of mitofusin 2 (Mfn2) and its downstream signaling pathway on glomerular mesangial cells (GMCs) proliferation in IgA nephropathy (IgAN),as well as the mechanism of action of Jixueca...
关键词:CENTELLA Glomerulonephritis IGA MESANGIAL CELLS Mitofusin 2 
Design and evaluation of glomerulus mesangium-targeted PEG-PLGA nanoparticles loaded with dexamethasone acetate被引量:2
《Acta Pharmacologica Sinica》2019年第1期143-150,共8页Sha Li Ying-chun Zeng Ke Peng Chang Liu Zhi-rong Zhang Ling Zhang 
the National Natural Science Foundation of China (Nos. 81473169 and 81130060).
Mesangial proliferative glomerulonephritis (MsPGN),one of the most common glomerulonephritis pathological types,often leads to end-stage renal disease over a prolonged period.But the current treatment of MsPGN is non-...
关键词:GLOMERULONEPHRITIS Mesangium MESANGIAL cells PEG-PLGA nanoparticles DEXAMETHASONE ACETATE 
Expression and mechanism of Long non-coding RNA ASncmtRNA-2 in high glucose treated human renal mesangial cells
《Journal of Hainan Medical University》2018年第14期9-12,共4页Hong-Xia Ma Wan-Yuan Yin PinWang 
Objective:To observe the expression of Long non-coding RNA antisense mitochondrial non-coding RNA-2 (ASncmtRNA-2) in high glucose (HG) treated human renal mesangial cells (HRMCs) and the role of ASncmtRNA-2 in oxidati...
关键词:Long NON-CODING RNA ANTISENSE MITOCHONDRIAL NON-CODING RNA-2 Human renal MESANGIAL cells DIABETIC NEPHROPATHY 
中医治疗系膜增生性肾小球肾炎近况被引量:3
《实用中医药杂志》2018年第1期132-133,共2页周少婷 甘兰岚 谭海丽 黄国东 
系膜增生性肾小球肾炎(mesangial proliferative glomerulonephritis,MsPGN)病理上表现以光镜下肾小球呈弥漫性系膜细胞增生和(或)系膜基质增多为特征的肾小球疾病[1],约占成人原发性肾小球疾病肾穿刺病例24.7%~30.3%[2]。根据免疫...
关键词:中医治疗 系膜基质 系膜细胞增生 MESANGIAL MSPGN 肾小球 保肾冲剂 免疫病理 气阴两虚证 系膜增生 
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