Supported by Monographic Research of Capital Traditional Chinese Medicine(No.3500-11723360)
OBJECTIVE: To investigate the effect of the clinical effective prescription of Qingre Lishi Yishen decoction(QRLS) on the activation of mesangial cells in immunoglobulin A nephropathy(IgAN) rats.METHODS: IgAN rat’s m...
Fibronectin glomerulopathy is a rare autosomal dominant inherited glomerular disease associated with massive deposition of fibronectin.We recently diagnosed fibronectin glomerulopathy in a 29-year-old woman presenting...
Supported by National Natural Science Foundation of China No.30740031,No.30871146;the New Century Excellent Talent of the Ministry of Education of China,No.NCET-06-0264
AIM:To investigate the role of insulin-like growth factor binding protein-7 (IGFBP-7) in the activation and transdifferentiation of hepatic stellate cells (HSC) in vitro.METHODS:Rat HSC-T6 cells were cultured in separ...
This work was supported by the National Natural Science Foundation of China (No 30270548) and the Natural Science Foundation of High Education of Jiangsu Province (No 07KJD310171). Xia LIU, Lei LV, and Yi-chun ZHU designed research; Xia LIU and Bei-bei TAO performed Western blotting and RT-PCR, respectively; Xia LIU and Lei LV analyzed data; Xia LIU and Yi-chun ZHU wrote the paper.
Aim: To investigate the effect of all-trans RA (atRA) on the increases in plasminogen activator inhibitor-1 (PAl-1) and fibronectin that are induced by transforming growth factor-β1 (TGF-β1) and angiotensin ...
As the progress of vascular surgery, artificial vessels have become the substitute for large and middle diameter vessels but have not for small diameter ones owing to thrombogenesis and occlusion within a short period...
Project supported by Fujian Provincial Science Foundation;No 2001Z029.
AIM: To study the preventive effect of recombinant human fibronectin (rhFN) polypeptide on hepatic failure in- duced by endotoxin in mice. METHODS: A cDNA fragment coding for Ile1363-Tyr1725 of human FN was inserted...
Project supported by the grants from the National Key Program of Basic Research (№ G2000056904), the Shanghai Science and Technology Committee, and the Health Science Center,Shanghai Second Medical University and Chinese Academy of Sciences.
AIM: To study the time course of the expression of stem cell marker and endothelial cell markers on human cord blood CD34^+ cells during in vitro differentiation process of endothelial progenitor cells (EPC). METHODS:...
Objective: To observe the expression of laminin and fibronectin in alkali burned corneas in rats.Methods: A total of 18 normal Wistar rats were randomly divided into 6 groups (n=3 in each group). For each rat, one eye...
OBJECTIVE: To study the effects of focal adhesion kinase (FAK) phosphorylation on smooth muscle cells (SMCs) adhesion and migration stimulated by fibronectin. METHODS: Adhesion and migration of cultured SMCs were stim...
Simple immune agar diffusion test was used to assay the contents of 12 plasma proteins in 70 cases of chronic pulmonary heart disease treated by Huang Qi Wu Wu Decoction (黄芪五物汤), with the other 70 cases who w...