LAMININ

作品数:141被引量:342H指数:10
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相关领域:医药卫生更多>>
相关作者:马美刚王国英钟世镇吴原秦建强更多>>
相关机构:第三军医大学哈尔滨医科大学中国医科大学重庆医科大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划广西医疗卫生重点科研课题广西壮族自治区自然科学基金更多>>
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The importance of laminin at the blood-brain barrier被引量:6
《Neural Regeneration Research》2023年第12期2557-2563,共7页Sebok K.Halder Arjun Sapkota Richard Milner 
the NIH RO1,No.NS103966 (to RM)。
The blood-brain barrier is a unique property of central nervous system blood vessels that protects sensitive central nervous system cells from potentially harmful blood components.The mechanistic basis of this barrier...
关键词:ASTROCYTES basement membrane blood vessels blood-brain barrier integrity DYSTROGLYCAN endothelial cells inflammation INTEGRINS LAMININ PERICYTES 
NDRG2在老年核性白内障晶状体中的表达变化研究
《现代生物医学进展》2023年第16期3196-3200,共5页刘冬瑞 宋凡倩 葛红岩 郭嫱 刘平 
黑龙江省卫生健康委科研项目(2019-039)。
目的:探索NDRG2基因在老年核性白内障晶状体组织中,随着核级增加的表达变化及可能的作用机制。方法:纳入2019年9月1日至2021年8月31日于哈尔滨医科大附属第一医院进行手术治疗的老年核性白内障患者的晶状体组织,依据Emery分级进行核分级...
关键词:NDRG2 Lamininγ 老年核性白内障 发病机制 衰老 
Synergy of human platelet lysate and laminin to enhance the neurotrophic effect of human adipose-derived stem cells
《Neural Regeneration Research》2022年第10期2200-2202,共3页Pietro G di Summa Srinivas Madduri 
supported by the Leenards Foundation for the economic support granted(to PGDS).
Despite the spontaneous regenerative capacity of the peripheral nervous system,clinical nerve repair often results in poor functional recovery with the high socio-economic burden.In presence of peripheral nerve injuri...
关键词:INJURIES DONOR SPITE 
p53 positively regulates the proliferation of hepatic progenitor cells promoted by laminin-521被引量:1
《Signal Transduction and Targeted Therapy》2022年第9期3592-3608,共17页Mingyang Ma Shuyao Hua Xiangde Min Liang Wang Jun Li Ping Wu Huifang Liang Bixiang Zhang Xiaoping Chen Shuai Xiang 
This work was supported by grants from National Natural Science Foundation of China(Nos.81200314,81572855);the State Key Project on Infection Diseases of China(2018ZX10723204-003);the Youth Incubation Fund of Tianjin Medical University General Hospital(No.ZYYFY2018017);Tianjin Key Medical Discipline(Specialty)Construction Project.
Hepatic progenitor cells(HPCs)hold tremendous potential for liver regeneration,but their well-known limitation of proliferation hampers their broader use.There is evidence that laminin is required for the proliferatio...
关键词:LAMININ PROGENITOR inhibited 
Observation of the Effect of Biofeedback Electrical Stimulation on PFD Model Rats
《外文科技期刊数据库(文摘版)医药卫生》2022年第8期159-164,共6页HEXianjie YANGJiahao HEJialiang WANGZhongliang LIUNa 
Objective: to explore the specific effect, degree and possible mechanism of biofeedback electrical stimulation intervention on the expression of characteristic indicators in Pelvic floor dysfunction (PFD) rats. Method...
关键词:pelvic floor dysfunction matrix metalloproteinase 2 hyaluronic acid LAMININ type collagen KNOT 
Biochemical composition of the glomerular extracellular matrix in patients with diabetic kidney disease
《World Journal of Diabetes》2022年第7期498-520,共23页María M Adeva-Andany Natalia Carneiro-Freire 
In the glomeruli,mesangial cells produce mesangial matrix while podocytes wrap glomerular capillaries with cellular extensions named foot processes and tether the glomerular basement membrane(GBM).The turnover of the ...
关键词:Diabetes Kidney disease GLYCOSAMINOGLYCANS Factor H Sialic acid LAMININ COLLAGEN Fibronectin-1 Extracellular matrix 
Microenvironmental stiffness mediates cytoskeleton re-organization in chondrocytes through laminin-FAK mechanotransduction被引量:3
《International Journal of Oral Science》2022年第2期182-191,共10页Chenchen Zhou Mengmeng Duan Daimo Guo Xinmei Du Demao Zhang Jing Xie 
supported by the National Natural Science Foundation of China(81771047 to Jing Xie,81901040,82171001 to C.Z.);by the Young Elite Scientist Sponsorship Program by CAST(2020QNR001)。
Microenvironmental biophysical factors play a fundamental role in controlling cell behaviors including cell morphology,proliferation,adhesion and differentiation,and even determining the cell fate.Cells are able to ac...
关键词:LAMININ mec STIFFNESS 
Royal Jelly Extract Accelerates Keratinocyte Proliferation, and Upregulates Laminin α3 and Integrin β1 mRNA Expression, via Akt/mTOR/HIF-1α Pathway被引量:2
《Journal of Cosmetics, Dermatological Sciences and Applications》2022年第2期83-94,共12页Akihiro Aioi 
Background: In the previous decade, various benefits and biological activities of royal jelly, applied in alternative and modern medicine, and cosmetics, have been reported. However, the effects of royal jelly extract...
关键词:Royal Jelly KERATINOCYTE PROLIFERATION Epidermal Basement Membrane Hypoxia-Inducible Factor-1 
Laminin 332-functionalized coating to regulate the behavior of keratinocytes and gingival mesenchymal stem cells to enhance implant soft tissue sealing被引量:1
《Regenerative Biomaterials》2022年第1期724-738,共15页Lipeng Liu Jing Wang Ying Li Bing Liu Wei Zhang Weikang An Qing Wang Boya Xu Lingzhou Zhao Chufan Ma 
supported by the National Natural Science Foundation of China(No.81970971);Shaanxi Key Research and Development Program(No.2022SF-179).
Peri-implant epithelial sealing is the first line of defense against external pathogens or stimuli;hence,an essential process to prevent peri-implantitis.Laminin 332(LN332)is the main component of the internal basal l...
关键词:PDLLA laminin 332 KERATINOCYTES gingival mesenchymal stem cells soft tissue sealing 
Semi-3D cultures using Laminin 221 as a coating material for human induced pluripotent stem cells
《Regenerative Biomaterials》2022年第1期775-793,共19页Yoshiki Nakashima Shinsuke Yoshida Masayoshi Tsukahara 
supported by Japan Agency for Medical Research and Development(AMED)under grant number JP22bm0104001.
It was previously believed that human induced pluripotent stem cells(hiPSCs)did not show adhesion to the coating material Laminin 221,which is known to have specific affinity for cardiomyocytes.In this study,we report...
关键词:human induced pluripotent stem cells(hiPSCs) regenerative medicine coating material CARDIOMYOCYTE therapeutic cells 
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