Synergy of human platelet lysate and laminin to enhance the neurotrophic effect of human adipose-derived stem cells  

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作  者:Pietro G di Summa Srinivas Madduri 

机构地区:[1]Department of Plastic,Reconstructive and Hand Surgery,University Hospital of Lausanne,University of Lausanne,Lausanne,Switzerland [2]Department of Surgery,Bioengineering and Neuroregeneration,University of Geneva,University Hospital Geneva,Geneva,Switzerland

出  处:《Neural Regeneration Research》2022年第10期2200-2202,共3页中国神经再生研究(英文版)

基  金:supported by the Leenards Foundation for the economic support granted(to PGDS).

摘  要:Despite the spontaneous regenerative capacity of the peripheral nervous system,clinical nerve repair often results in poor functional recovery with the high socio-economic burden.In presence of peripheral nerve injuries and when distal nerve transfers are not possible,nerve autografts,are the solution of choice to cross a critical nerve gap.However,these are associated with donor site morbidity and offer only suboptimal functional recovery.Thus,the need to improve the rate of effective regeneration has directed research attention towards stem cell therapy and nerve tissue engineering.

关 键 词:INJURIES DONOR SPITE 

分 类 号:R741[医药卫生—神经病学与精神病学]

 

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