PDLLA

作品数：129被引量：343H指数：9
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基于Micro-CT评价超声骨焊接技术PDLLA材料对骨愈合性能的影响
《新疆医科大学学报》2024年第5期681-686,共6页阿曼妮萨罕·加帕尔 阿依达娜·乌拉尔别克 贺琦 刘雪 孜尔达·阿依丁 杨一帆 凌彬 
新疆维吾尔自治区区域协同创新专项项目(2020E02130)。
目的采用微焦点断层扫描(Micro-CT)评价超声骨焊接技术应用过程中超声震荡产热作用下PDLLA材料对骨愈合性能的影响。方法选择SPF级雄性新西兰大白兔36只,随机分为超声骨焊接技术辅助PDLLA材料组(A组)、拧入技术辅助PDLLA材料组(B组)、...
关键词：超声骨焊接技术 PDLLA MICRO-CT 兔下颌骨缺损模型 骨愈合 
超声波焊接技术应用PDLLA接骨系统固定兔下颌骨骨折的有限元分析
《新疆医科大学学报》2024年第4期506-511,共6页阿依达娜·乌拉尔别克 阿曼妮萨罕·加帕尔 凌彬 
新疆维吾尔自治区区域协同创新专项项目(2020E02130)。
目的探讨两种不同固定方式对兔下颌骨进行固定后的应力及位移影响。方法健康成年新西兰大白兔,雄性,2~4月龄,体重3.0~3.5 kg,制取兔下颌骨并造骨折模型。基于兔下颌骨标本Micro CT数据,使用软件进行处理后构建兔下颌骨骨折有限元模型。...
关键词：超声波焊接技术 下颌骨骨折 有限元分析 
PDLLA length on anti-breast cancer efficacy of acid-responsive self-assembling mPEG-PDLLA–docetaxel conjugates
《Chinese Chemical Letters》2023年第9期225-229,共5页Tao Liu Hui Zou Jingqing Mu Xi Zhang Guohua Liu Na Yu Bo Yuan Xiaoyong Yuan Xingjie Liang Shutao Guo 
financially supported by National Natural Science Foundation of China(Nos.32171386 and 32201157);the Natural Science Foundation of Tianjin of China(No.21JCZDJC01250);the China Postdoctoral Science Foundation(No.2021M690793)。
Engineering small-molecule drugs into nanoparticulate formulations provides an unprecedented opportunity to improve the performance of traditional chemo drugs,but suffers from poor compatibility between drugs and nano...
关键词：NANOMEDICINE PRODRUG DOCETAXEL mPEG-PDLLA Acid-sensitive 
Effect of PEG Incorporation on Physicochemical and in vitro Degradation of PLLA/PDLLA Blends:Application in Biodegradable Implants
《Journal of Renewable Materials》2023年第7期3043-3056,共14页Mochamad Chalid Gifrandy Gustiraharjo Azizah Intan Pangesty Alyssa Adyandra Yudan Whulanza Sugeng Supriadi 
Funding Statement:This work was supported by Universitas Indonesia under Grant PUTI 2020(No.NKB-4325/UN2.RST/HKP.05.00/2020).
Polyethylene glycol(PEG)was added at different concentrations to the blend of poly(L-lactic acid)(PLLA)and poly(D,L-lactic acid)(PDLLA)to tailor the properties.The differential scanning calorimetry(DSC)measurement sho...
关键词：PLLA PDLLA PEG CRYSTALLINITY degradation 
载美洲大蠊有效部位CII-3 PDLLA微球的制备及制剂学评价被引量：1
《广东化工》2023年第9期77-81,76,共6页袁近津 王亚伦 朱站站 王天龙 王绍仙 李婧炜 
采用乳化溶剂挥发法,以PEG修饰的PDLLA为原材料,制备载美洲大蠊有效部位CII-3 PDLLA微球。通过单因素试验以及正交试验优化制备工艺,并对微球进行表征,通过对微球的体外释放规律和稳定性进行初步研究。结果显示,所制备的微球载药量为1.2...
关键词：美洲大蠊 微球 单因素试验 正交试验 体外释放 
An injectable mPEG-PDLLA microsphere/PDLLA-PEG-PDLLA hydrogel composite for soft tissue augmentation
《Chinese Chemical Letters》2022年第5期2486-2490,共5页Yue Pan Yao Xiao Ying Hao Kun Shi Meng Pan Zhiyong Qian 
supported by the National Natural Science Foundation of China(Nos.NSFC31930067,NSFC31771096,and NSFC31525009);the National Key Research and Development Pro-gram of China(No.2017YFC1103502);the 1·3·5 Project for Disci-plines of Excellence,West China Hospital,Sichuan University(No.ZYGD18002)。
Injectable filling material is a simple and efficient method for soft tissues reconstruction and is extremely popular in not only plastic surgery but also cosmetic industry.However,there is a lack of soft tissue fille...
关键词：Soft tissue augmentation mPEG-PDLLA MICROSPHERES HYDROGEL Collagenogenesis 
钛表面PDLLA-LN5复合涂层的构建及对角质形成细胞生物学行为的影响被引量：1
《实用口腔医学杂志》2022年第2期168-173,共6页刘利鹏 安维康 郑亚飞 张薇 王青 马楚凡 
国家自然科学基金(编号:81970971)。
目的:在纯钛表面构建聚消旋乳酸-层粘连蛋白5(PDLLA-LN5)复合缓释涂层,观察对角质形成细胞生物学行为的影响。方法:以纯钛为基底(P组),表面滴加PDLLA(PDLLA组),通过层层组装-物理吸附的方法制备载LN5的PDLLA涂层(PDLLA/LN5组),扫描电镜...
关键词：钛种植体 层粘连蛋白5 缓释涂层 角质形成细胞 
Laminin 332-functionalized coating to regulate the behavior of keratinocytes and gingival mesenchymal stem cells to enhance implant soft tissue sealing被引量：1
《Regenerative Biomaterials》2022年第1期724-738,共15页Lipeng Liu Jing Wang Ying Li Bing Liu Wei Zhang Weikang An Qing Wang Boya Xu Lingzhou Zhao Chufan Ma 
supported by the National Natural Science Foundation of China(No.81970971);Shaanxi Key Research and Development Program(No.2022SF-179).
Peri-implant epithelial sealing is the first line of defense against external pathogens or stimuli;hence,an essential process to prevent peri-implantitis.Laminin 332(LN332)is the main component of the internal basal l...
关键词：PDLLA laminin 332 KERATINOCYTES gingival mesenchymal stem cells soft tissue sealing 
Small extracellular vesicles in combination with sleep-related circRNA3503:A targeted therapeutic agent with injectable thermosensitive hydrogel to prevent osteoarthritis被引量：10
《Bioactive Materials》2021年第12期4455-4469,共15页Shi-Cong Tao Ji-Yan Huang Yuan Gao Zi-Xiang Li Zhan-Ying Wei Helen Dawes Shang-Chun Guo 
The present study was supported by the National Natural Science Foundation of China(grant numbers 81301589,81802226,81871834 and 82072530);the Shanghai Pujiang Program(grant number 2019PJD038);Shanghai“Rising Stars of Medical Talent”Youth Development Program(Youth Medical Talents-Specialist Program);the Shanghai Jiao Tong University K.C.Wong Medical Fellowship Fund.
Osteoarthritis(OA),characterized by chondrocyte apoptosis and disturbance of the balance between catabolism and anabolism of the extracellular matrix(ECM),is the most common age-related degenerative joint disease worl...
关键词：Extracellular vesicles EXOSOMES Circular RNAs PDLLA-PEG-PDLLA 
PDLLA/β-TCP/HA/CHS/NGF Sustained-release Conduits for Peripheral Nerve Regeneration
《Journal of Wuhan University of Technology(Materials Science)》2021年第4期600-606,共7页YAN Xiumei WANG Jing HE Qundi XU Haixing TAO Junyan KORAL Kelly LI Kebi XU Jingyi WEN Jing HUANG Zhijun XU Peihu 
Funded by the Chinese National Natural Science Foundation (No. 51572206);the National Innovation and Entrepreneurship Training Program for College (Nos. 202110497032, 202110497033, and S202110497080)。
Using nerve guide conduits (NGCs) to promote the regeneration of PNI is a feasible alternative to autograft.Compared with NGCs made of single material,composite NGCs have a greater development prospect.Our previous re...
关键词：SUSTAINED-RELEASE composite nerve conduits peripheral nerve regeneration 
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