SUSTAINED-RELEASE

作品数：64被引量：98H指数：5
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相关作者：潘卫三梅康康胡容峰许向阳臧蕾更多>>
相关机构：沈阳药科大学上海交通大学中国药科大学安徽中医学院更多>>
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相关基金：国家自然科学基金广东省自然科学基金国家高技术研究发展计划湖北省自然科学基金更多>>
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Synthesis and in vitro/in vivo assessment of sustained-release oral oseltamivir phosphate suspension
《Journal of Chinese Pharmaceutical Sciences》2025年第3期269-283,共15页Yuanrong Xin Yutian Dou Xiaolin Chen Yingshu Feng Xuesheng Liu Caleb Kesse Firempong Dan Yang Hongfei Liu Haibing He 
2023 Nantong Jianghai Talents Project;2023 Nantong Social Livelihood Science and Technology Plan;2021 Jurong Social Development Science&Technology Program(Grant No.ZA42109);2022 New Drugs and Platform Enhancement Project of the Yangtze Delta Drug Advanced Research Institute;China Postdoctoral Science Foundation(Grant No.2020M681532);Jiangsu Planned Projects for Postdoctoral Research Funds(Grant No.2020Z209);Natural Science Research Projects of Universities in Jiangsu Province(Grant No.20KJD350001)。
Oseltamivir phosphate(OP),renowned as one of the most effective drugs for influenza treatment,encounters several challenges,including poor stability,difficulty in swallowing,and a bitter taste,thereby limiting its com...
关键词：Oseltamivir phosphate SUSTAINED-RELEASE Ion exchange resin SUSPENSION 
Performance analysis of nanostructured lipid carriers for chemical sunscreen agents
《日用化学工业(中英文)》2025年第2期185-193,共9页Xiaoyu Li Jianping Jiang Lifeng Xiao 
广东省普通高校重点领域专项(2021ZDZX2076)。
Nanolipid carriers and traditional emulsion containing chemical sunscreens were prepared using emulsification combined with ultrasonic technology.The nanolipid carriers showed superior performance in sunscreen encapsu...
关键词：nano lipid carrier sunscreen agents PHOTOSTABILITY in vitro sustained-release properties extracorporeal permeability 
Intra-articular sustained-release of pirfenidone as a disease-modifying treatment for early osteoarthritis
《Bioactive Materials》2024年第9期255-272,共18页Xiaobo Zhu Mingde Cao Kejia Li Yau-Tsz Chan Hon-Fai Chan Yi-Wah Mak Hao Yao Jing Sun Michael Tim-Yun Ong Kevin Ki-Wai Ho Chien-Wei Lee Oscar Kuang-Sheng Lee Patrick Shu-Hang Yung Yangzi Jiang 
supports from all parties during the Covid-19 pandemic;supported by(1)the National Key R&D Program of China(Project No.2019YFA0111900 to YJ),which is financed by the Ministry of Science and Technology of the People’s Republic of China(MOST,China);supported by a grant from the NSFC/RGC Joint Research Scheme sponsored by the Research Grants Council of the Hong Kong Special Administrative Region,China and the National Natural Science Foundation of China(Project No.N_CUHK483/22 to YJ);the Center for Neuromusculoskeletal Restorative Medicine[CNRM at InnoHK,to YJ,HC,PY]by Innovation and Technology Commission(ITC)of Hong Kong SAR,China;the Natural Science Foundation of China(Project No 82302728 to XZ);The Chinese University of Hong Kong.
Osteoarthritis(OA)is a major clinical challenge,and effective disease-modifying drugs for OA are still lacking due to the complicated pathology and scattered treatment targets.Effective early treatments are urgently n...
关键词：TGFβ1 signaling OSTEOARTHRITIS Subchondral bone Pirfenidone DMOAD 
Chemical oxygen demand oxidation via sustained-release persulfate balls: a rate-compatibility study of flow velocity, releasing, and oxidation
《Journal of Zhejiang University-Science A(Applied Physics & Engineering)》2024年第9期749-762,共14页Bate BATE Danting ZHANG Jianshe YE Min XIA Yixin YANG Shuai ZHANG 
Ministry of Science and Technology of China(Nos.2019YFC1805002 and 2018YFC1802300);National Natural Science Foundation of China(Nos.42177118 and 51779219);Basic Science Center Program for Multiphase Evolution in Hypergravity of the National Natural Science Foundation of China(No.51988101);Overseas Expertise Introduction Center for Discipline Innovation(No.B18047),China.
Identification of chemical oxygen demand(COD)in municipal solid waste(MSW)landfill leachates is a challenging problem.This paper investigated the feasibility of using sodium persulfate(PS),a strong oxidant,as a permea...
关键词：Chemical oxygen demand(COD) Sodium persulfate(PS) Sustained-release balls Permeable reactive barrier(PRB) Fe(II)-loaded activated carbon(Fe-AC) 
Use of a pH-responsive imatinib mesylate sustained-release hydrogel for the treatment of tendon adhesion by inhibiting PDGFRβ/CLDN1 pathway
《Bioactive Materials》2024年第8期124-136,共13页Sa Pang Rongpu Wu Wenxin Lv Jian Zou Yuange Li Yanhao Li Peilin Zhang Xin Ma Yi Wang Shen Liu 
supported by the National Natural Science Foundation of China(No.81902234,82172408 and 81772314);Principle Investigator Innovation Team of Both Shanghai Sixth People’s Hospital and Shanghai Institute of Nutrition and Health,Shanghai Jiao Tong University Medical College“Two-hundred Talent”Program(No.20191829);The Second Three-Year Action Plan for Promoting Clinical Skills and Clinical Innovation in Municipal Hospitals of Shanghai Shenkang(No.SHDC2020CR4032);Shanghai Engineering Research Center for Orthopaedic Material Innovation and Tissue Regeneration(No.20DZ2254100);Original Exploration project(22ZR1480300);Outstanding Academic Leaders(Youth)project(21XD1422900)of Shanghai Science and Technology Innovation Action Plan.We are also grateful to Professor Jun Qin(Shanghai Institute of Nutrition and Health,Chinese Academy of Sciences)for his technical assistance.
Adhesion after tendon injury,which can result in limb movement disorders,is a common clinical complication;however,effective treatment methods are lacking.Hyaluronic acid hydrogels are a new biomedical material used t...
关键词：HYDROGEL ZIF-8 Peritendinous adhesion Imatinib mesylate Claudin 1 
Boosted sustained-release with iron-based MOF-derived mesoporouscarbon-spheres as a nitroimidazole drugs carrier
《Particuology》2024年第3期269-280,共12页Danping Wu Jiaying Zou Junyi Chen Yan Li Na Ma Wei Dai 
the National Natural Science Foundation of China(grant No.22178325).
Metal-organic framework(MoF)with a buildable internal structure has aroused great interest focus as self-sacrificing precursors of porous carbon(PC).However,as a drug carrier,the MOF-derived PC developed thus far are ...
关键词：ORNIDAZOLE METRONIDAZOLE Carbon spheres Sustained-release performance Biocompatibility 
pH-sensitive KHA/CMC-Fe^(3+)@CS hydrogel loading and the drug release properties of riboflavin被引量：1
《Particuology》2024年第3期13-23,共11页Jie Song Xi Li Yuhua Niu Lijun Chen Zhiqiang Wei Yidan Li Youqian Wang 
supported by the National Natural Science Foundation of China(grant No.51803114);Shaanxi Province Key R&D Program(grant No.2022NY-195);Xi'an City Innovation Capability Strong Foundation Plan-Agricultural Technology R&D(grant No.21NYYF0025);Shaanxi Province Education Department Service Local Special Program Project(grant No.22jcO15);Shaanxi Province Key R&D Program(grant No.2020SF-411);Industry-University-Research Cooperation Project of Yulin Science and Technology Bureau(grant No.CXY-2020-086);National Key R&D Projects in 2021(grant No.2021YFC1808900).
To improve drug utilization,reduce the drug administration frequency,increase the release time,and reduce the drug side effects in the human body,we prepared(KHA/CMC-Fe^(3+))@CS hydrogel spheres using green and natura...
关键词：Potassium humate Hydrogel spheres PH-SENSITIVE Drugsustained-release Drug release model 
Biodegradable implants based on photo-cross-linked aliphatic polycarbonates for long-acting contraception
《Journal of Materials Science & Technology》2023年第25期129-141,共13页Zhipeng Hou Wei Xu Siwen Chen Jing Guo Peng Li Jianshe Hu Liqun Yang Jing Chen 
sponsored by the Natural Science Foundation of Liaoning Province(Nos.2022-YGJC-69,2021-BS-110);the support program for excellent young scholars of China Medical University.
In this study,a new class of biodegradable contraceptive implants was prepared via the UV irradiation molding method,among which,progestin levonorgestrel(LNG)was used as a model drug.Photo-cross-linked aliphatic polyc...
关键词：Aliphatic polycarbonates Photo-cross-linked LEVONORGESTREL Contraceptive implants Anti-fertility effects SUSTAINED-RELEASE 
Rapidly separating dissolving microneedles with sustained-release colchicine and stabilized uricase for simplified long-term gout management被引量：2
《Acta Pharmaceutica Sinica B》2023年第8期3454-3470,共17页Yao Yang Zimu Li Ping Huang Jiachan Lin Jinyuan Li Kexin Shi Jiahui Lin Jingwen Hu Zhuoxian Zhao Yongkang Yu Hongzhong Chen Xiaowei Zeng Lin Mei 
the financial support from the National Natural Science Foundation(NOs.32071342,and 82272154,China);Guangdong Special Support Program(NO.2019TQ05Y209,China);the Natural Science Foundation of Guangdong Province(NO.2023A1515012015,China);Tianjin Science Fund for Distinguished Young Scholars(NO.22JCJQJC00120,China);Natural Science Foundation of Tianjin(The Basic Research Cooperation Special Foundation of Beijing-Tianjin-Hebei Region,NO.22JCZXJC00060,China);the Fundamental Research Funds for the Central Universities(NO.2021-RC310-005,China);Technology&Innovation Commission of Shenzhen Municipality(NOs.JCYJ20220818102810023,JCYJ20190807153601667,and JCYJ20210324124402006,China);Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(NOs.2021-I2M-1e058,and 2022-I2M-2-003,China)。
Despite growing prevalence and incidence,the management of gout remains suboptimal.The intermittent nature of the gout makes the long-term urate-lowering therapy(ULT)particularly important for gout management.However,...
关键词：MICRONEEDLES COLCHICINE SUSTAINED-RELEASE URICASE Liposome Transdermal administration Gout management Long-term urate-lowering therapy 
Combustion Characteristics of Solid Sustained-Release Energetic Materials
《Journal of Beijing Institute of Technology》2023年第4期463-476,共14页Bingxu Qiao Zengyou Liang Fudi Liang Tongtong Zhou 
A solid sustained-release energetic material sample,an eruption device and a complete test system were prepared further to analyse the combustion characteristics of solid sustainedrelease energetic materials.The high-...
关键词：solid sustained-release energetic materials high-temperature heat flux combustion wave structure high-temperature jet structure mass burning rate formula numerical simulation 
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