CARDIOMYOCYTE

作品数：183被引量：784H指数：14
导出分析报告
相关领域：医药卫生更多>>
相关作者：单志新周兆年郭东林胡崇家曾繁典更多>>
相关机构：中国科学院上海生命科学研究院同济医科大学上海医科大学附属中山医院上海市第十人民医院更多>>
相关期刊：更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金中国博士后科学基金更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Disruption of mitochondrial DNA integrity in cardiomyocyte injury upon ischemia/reperfusion
《Genes & Diseases》2025年第3期180-193,共14页Shengnan Hu Xueying Tang Fangrui Zhu Chen Liang Sa Wang Hongjie Wang Peifeng Li Yuzhen Li 
supported by grants from the National Natural Science Foundation of China(No.81970246,81470437).
Mitochondria serve as the energy provider and enable life activities,and they are the only organelles containing extra-chromosomal DNA.Each mitochondrion contains multiple copies of its genome,which is usually referre...
关键词：CARDIOMYOCYTE ISCHEMIA/REPERFUSION mtDNA Package Repair REPLICATION TRANSCRIPTION 
TRADD-mediated pyroptosis contributes to diabetic cardiomyopathy
《Acta Pharmacologica Sinica》2025年第4期940-950,共11页Yang-yang Zheng Dan-ning Shen Xiao-lu Peng Wen-qing San Qian-you Zhou Sheng-ju Yang Guo-liang Meng Jia-hai Shi Yun Chen 
supported by the National Natural Science Foundation of China(82200313,82070280,82270418,82370253);the“333 Project”of Jiangsu Province(2022-3-16-670);the Six Talent Peaks Project in Jiangsu Province(2018-WSN-062);Jiangsu Provincial Research Hospital(YJXYY202204);Innovation Team Project of Affiliated Hospital of Nantong University(XNBHCX31773).
Regulated cell death like pyroptosis is one vital cause of diabetic cardiomyopathy(DCM),which eventually leads to heart failure.Tumor necrosis factor(TNF)receptor-associated death domain protein(TRADD)is an adapter pr...
关键词：diabetic cardiomyopathy PYROPTOSIS TRADD XBP1 Apostatin-1 CARDIOMYOCYTE 
Partial Regulation of Ketone Metabolism by Hypoxia in H9C2 Cardiomyocytes
《Current Medical Science》2025年第1期25-34,共10页Li-zhen Chen Hong-qing Chen Xin-yuan Zhang Shuang Ling Jin-wen Xu 
supported by the Specialized Research Fund for the National Natural Science Foundation of China(No.81973511).
Objective Hypoxia plays a critical role in the pathophysiology of cardiomyopathy,myocardial infarction,and heart failure.Promoting ketone metabolism has been shown to be beneficial for myocardial cells under hypoxic c...
关键词：Ketone metabolism HYPOXIA Gene expression Succinyl-CoA CARDIOMYOCYTE 
Microfluidic platforms for monitoringcardiomyocyte electromechanical activity
《Microsystems & Nanoengineering》2025年第1期23-44,共22页Wei Wang Weiguang Su Junlei Han Wei Song Xinyu Li Chonghai Xu Yu Sun Li Wang 
supported by the National Natural Science Foundation of China(NO.62371267,62121003);Key R&D Program of Shandong Province(Major innovation project)(2022CXGC020501);Science,Education and Industry Integration Innovation Pilot Project from Qilu University of Technology(Shandong Academy of Sciences)(NO.2022JBZ02-01);Research Leader Studio in Colleges and Universities of Jinan(NO.2021GXRC083);Innovation Team of Organ-on-a-Chip Manufacturing Key Technologies(NO.202333015,Funded by Jinan Science and Technology Bureau);Young Innovative Talents Introduction&Cultivation Program for Colleges and Universities of Shandong Province(Granted by Department of Education of Shandong Province,Sub-Title 1:Innovative Research Team of High-Performance Integrated Device,Sub-Title 2:Innovative Research Team of Advanced Energy Equipment);Shandong Provincial Natural Science Foundation(ZR2023QH405)。
Cardiovascular diseases account for ~40% of global deaths annually. This situation has revealed the urgent need forthe investigation and development of corresponding drugs for pathogenesis due to the complexity of res...
关键词：cardiac drug screeningand detection techniques microfluidic platforms investigation development corresponding drugs pathogenesis disease modeling accurate fluid control cardiovascular diseases vitro cardiomyocyte model 
Mitochondrial‑to‑nuclear communications through multiple routes regulate cardiomyocyte proliferation
《Cell Regeneration》2024年第1期379-382,共4页Xinhang Li Yalin Zhu Pilar Ruiz‑Lozano Ke Wei 
Key Research and Development Program,Ministry of Science and Technology of China(2018YFA0800104);National Natural Science Foundation of China(92168205,32070823);Fundamental Research Funds for the Central Universities(22120230471).
The regenerative capacity of the adult mammalian heart remains a formidable challenge in biological research.Despite extensive investigations into the loss of regenerative potential during evolution and development,un...
关键词：MITOCHONDRIA CARDIOMYOCYTE Proliferation FAO Cpt1b αKG H3k4me3 Mrps5 UPRmt ATF4 
Emerging biotechnologies for screening electromechanical signals of cardiomyocytes
《Aggregate》2024年第6期6-22,共17页Si Tang Lingyu Sun Huiyao Shi Kaixuan Wang Jialin Shi Chanmin Su Yuanjin Zhao Lianqing Liu 
Youth Innovation Promotion Association of the Chinese Academy of Sciences,Grant/Award Number:2021197;National Natural Science Foundation of China,Grant/Award Numbers:61925307,61927805,62127811;National Key Research and Development Program of China,Grant/Award Number:2021YFB3201600。
Cardiac diseases threaten human health and burden the global healthcare system.Cardiomyocytes(CMs)are considered the ideal model for studying the signal transduction and regulation of cardiac systems.Based on the prin...
关键词：biosensing platform CARDIOMYOCYTE electrical signal mechanical signal 
Integrated nanoporous electroporation and sensing electrode array for total dynamic time-domain cardiomyocyte membrane resealing assessment
《Bio-Design and Manufacturing》2024年第6期972-982,共11页Weiqin Sheng Ying Li Chunlian Qin Zhonghai Zhang Yuxiang Pan Zhicheng Tong Chong Teng Xinwei Wei 
supported by the Zhejiang Provincial Natural Science Foundation of China(No.LQ23E010004);the National Key Research and Development Program of China(No.2021YFB3200801)。
Intracellular electrophysiological research is vital for biological and medical research.Traditional planar microelectrode arrays(MEAs)have disadvantages in recording intracellular action potentials due to the loose c...
关键词：Nanoporous electrode array(NPEA) ELECTROPORATION Intracellular potential recording CARDIOMYOCYTE Membrane resealing 
Zhuangtongyin Ameliorates Cardiomyocyte Pyroptosis in Rats with Coronary Heart Disease by Regulating Caspase-1
《Journal of Biosciences and Medicines》2024年第11期94-108,共15页Shumin Zhang Hanqing Tang Xianfeng He Xuqing Zhang Weizhen Wei Wenchong Wang Jinying Wang 
Background: Recent studies have demonstrated that pyroptosis has an important impact on the pathological process of many cardiovascular diseases, and inhibiting this process can significantly reduce pathological damag...
关键词：Zhuangtongyin Coronary Heart Disease CASPASE-1 PYROPTOSIS INFLAMMATION 
Cardiomyocyte-specific knockout of ADAM17 alleviates doxorubicin-induced cardiomyopathy via inhibiting TNFα-TRAF3-TAK1-MAPK axis
《Signal Transduction and Targeted Therapy》2024年第11期5217-5236,共20页Lin Xie Fei Xue Cheng Cheng Wenhai Sui Jie Zhang Linlin Meng Yue Lu Wenjing Xiong Peili Bu Feng Xu Xiao Yu Bo Xi Lin Zhong Jianmin Yang Cheng Zhang Yun Zhang 
supported by grants of the National Natural Science Foundation of China(Nos.82000411,82030051,82241203,81920108003 and 81970366);State Key R&D Program of China(2021YFF0501403);Key R&D Program of Shandong Province(2021SFGC0503,2021ZLGX02,2021ZDSYS05,2020ZLYS05);Shandong Provincial Natural Science Foundation(ZR2020QH023);the Taishan Scholars Program of Shandong Province(C.Z.);China Postdoctoral Science Foundation(2023M742124);Postdoctoral Innovation Talents Support Program(BX20230210).
The pathogenesis of doxorubicin-induced cardiomyopathy remains unclear.This study was carried out to test our hypothesis that ADAM17 aggravates cardiomyocyte apoptosis induced by doxorubicin and inhibition of ADAM17 m...
关键词：DOXORUBICIN CARDIOMYOPATHY markedly 
Lovastatin modulation of YAP/TAZ signaling on cardiomyocyte autophagy and mitochondrial damage in myocardial I/R injury
《BIOCELL》2024年第10期1489-1501,共13页KAITIAN ZHANG MINGZHU LI JIANPING ZHANG JINFENG LI KUNLANG LI HUANQIAN LU JINYAN LV 
Objective:Studies have demonstrated that administering statins promptly following myocardial ischemia/reperfusion(MI/R)can confer cardioprotective benefits.This study investigates whether Lovastatin can modulate the Y...
关键词：MI/R injury LOVASTATIN YAP/TAZ signaling pathway AUTOPHAGY Mitochondrial damage 
全选清除导出
共19页<12345678910>
检索报告 对象比较 聚类工具 使用帮助 返回顶部