LIPOPOLYSACCHARIDES

作品数：99被引量：451H指数：12
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相关机构：浙江大学山西医科大学中国医科大学附属第一医院第三军医大学大坪医院更多>>
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Understanding the mechanism underlying the anti-inflammatory effect of dietary flavonoids on IBD:a focus on gut microbiota and its metabolites involved in SCFA,bile acid,tryptophan and lipopolysaccharides
《Food Science and Human Wellness》2025年第2期385-403,共19页Huihui Xiong Hui Chen Lingli Chen Kehui Ouyang Suyun Lin Wenjun Wang 
supported by grants from the National Natural Science Foundation of China(31560459);Jiangxi Provincial Natural Science Foundation(20224ACB205014);The Double Thousands Talents Plan of Jiangxi(jxsq2018102075,jxsq2018102076)。
Inflammatory bowel disease(IBD)is a chronic gastrointestinal disease with a high incidence.Treatment for IBD includes medications and diet,and common anti-inflammatory medications have limitations like drug resistance...
关键词：Dietary flavonoids Inflammatory bowel disease Gut microbiota METABOLITES Mechanisms 
Gut microbiota differences,metabolite changes,and disease intervention during metabolic-dysfunction-related fatty liver progression
《World Journal of Hepatology》2025年第3期50-66,共17页Jian-Zhong Shu Yu-Han Huang Xiao-Hong He Feng-Ying Liu Qian-Qian Liang Xue-Tong Yong Yong-Fang Xie 
Supported by Natural Science Foundation of Chongqing,No.cstc2021jcyj-msxmx0848;Chongqing Bishan Scientific Research Project,No.BSKJ2022006;National Natural Science Foundation of China,No.81773954;National College Students Innovation and Entrepreneurship Program,No.202310617015.
In the current era,metabolic dysfunction-associated steatotic liver disease(MASLD)has gradually developed into a major type of chronic liver disease that is widespread globally.Numerous studies have shown that the gut...
关键词：Metabolic dysfunction-associated steatotic liver disease Gut microbiota Short-chain fatty acids Bile acids LIPOPOLYSACCHARIDES PROBIOTICS 
A rat model of adenoid hypertrophy constructed by using ovalbumin and lipopolysaccharides to induce allergy, chronic inflammation, and chronic intermittent hypoxia
《Animal Models and Experimental Medicine》2025年第2期353-362,共10页Anqi Liu Yixing Zhang Yan Lin Xuejun Li Shuming Wang Wenyan Pu Xiuxiu Liu Zhiyan Jiang Zhen Xiao 
This work was financially supported by the National Natural Science Foundation of China(grant number:8217150152);the Clinical Science and Technology Innovation Project of Shanghai Shenkang Hospital Development Center(grant number:SHDC12021102);the Shanghai Three-Year Action Plan to Further Accelerate the Development of Traditional Chinese Medicine Inheritance and Innovation(grant number:ZY(2021-2023)-0209-05).
Background:Adenoid hypertrophy(AH)is a common pediatric disease that signifi-cantly impacts the growth and quality of life of children.However,there is no replica-ble and valid model for AH.Methods:An AH rat model was...
关键词：allergic rhinitis hypoxia nasopharynx-associated lymphoid tissue rat model of adenoid hypertrophy upper respiratory inflammation 
Study on the antipyretic effect of pushing Tianheshui in young rabbits: focus on the α-MSH-mediated cAMP/PKA/NF-κB signaling pathway
《Journal of Acupuncture and Tuina Science》2024年第6期447-453,共7页HUANG Yumei WANG Dejun WANG Wei GAO Juan CHEN Liwei 
湖南省中医药管理局科研项目,No.A2023022;湖南中医药大学校级科研项目,No.2024XJZA006;湖南省教育厅科研项目,No.22A0277。
Objective:To explore the antipyretic effect and partial mechanism of the pushing Tianheshui manipulation on lipopolysaccharide(LPS)-induced fever in young New Zealand rabbits.Methods:Thirty 50-day-old New Zealand rabb...
关键词：TUINA Massage Manual Therapies Pushing Tianheshui LIPOPOLYSACCHARIDES FEVER Rabbits 
Molecular Mechanism of Polysaccharides Extracted from Chinese Medicine Targeting Gut Microbiota for Promoting Health被引量：1
《Chinese Journal of Integrative Medicine》2024年第2期171-180,共10页ZHAO Wen-xiao WANG Tong ZHANG Ya-nan CHEN Qian WANG Yuan XING Yan-qing ZHENG Jun DUAN Chen-chen CHEN Lijun ZHAO Hai-jun WANG Shijun 
Supported by the National Natural Science Foundation of China(No.81903947);the Key Research and Development Project of Shandong Province,China(No.2019GSF108209);Key Basic Research of the Natural Science Foundation of Shandong Province,China(No.ZR2019ZD23);Shandong University Youth Innovative Talent Introduction Project(LJRZ 2019,No.9-201)。
The accumulating evidence revealed that gut microbiota plays an important role in pathological process of disease including obesity,type 2 diabetes mellitus,heart failure,and non-alcoholic fatty liver disease.Polysacc...
关键词：Chinese medicine POLYSACCHARIDES gut microbiota short-chain fatty acids LIPOPOLYSACCHARIDES gut-organaxis synergistic actions 
Lipopolysaccharides protect mesenchymal stem cell against cardiac ischemia-reperfusion injury by HMGB1/STAT3 signaling
《Journal of Geriatric Cardiology》2023年第11期801-812,共12页Jing-Yi WEN Hui-Xi PENG Dan WANG Zhi-Min WEN Yu-Tong LIU Jian QU Hong-Xuan CUI Yu-Ying WANG Yan-Lin DU Ting WANG Cong GENG Bing XU 
supported by grants from the Natural Science Foundation of Liaoning Province(No.2023-MS-268);Educational Committee Foundation of Liaoning Province(LJKZ0868);Funds for young and middle-aged disciplinary backbones of the Second Hospital of Dalian Medical University(No.dy2yxkgg 202002);partially supported by United Fund of the Second Hospital of Dalian Medical University and Dalian Institute of Chemical physics Chinese Academy of Sciences(No.UF-QN-202005).
BACKGROUND Myocardial ischemia-reperfusion(I/R) is a serious and irreversible injury. Bone marrow-derived mesenchymal stem cells(MSCs) is considered to be a potential therapy for I/R injury due to the paracrine effect...
关键词：STAT3 HMGB1 ISCHEMIA 
Targeting Gut Microbiota for the Treatment of Primary Biliary Cholangitis:From Bench to Bedside
《Journal of Clinical and Translational Hepatology》2023年第4期958-966,共9页Li Zhang Ling Yang Huikuan Chu 
This study was supported by the National Natural Science Foundation of China(No.82000561 to HC,No.81974078,81570530,and 81370550 to LY);Natural Science Foundation of Hubei Province(No.2019ACA133 to LY);the Science Foundation of Union Hospital(No.2021xhyn005 to HC).
Primary biliary cholangitis(PBC)is a complex cholestatic liver disease with an unresolved etiology.The gut microbiota is composed of a dynamic community of bacteria,archaea,fungi,and viruses that have a key role in ph...
关键词：Primary biliary cholangitis Gut microbiota LIPOPOLYSACCHARIDES Bile acids PROBIOTICS Fecal microbiota transplantation 
Protective mechanisms of Tuina therapy against lipopolysaccharide-induced fever in young rabbits based on untargeted metabolomics analysis被引量：1
《Journal of Traditional Chinese Medicine》2023年第4期725-733,共9页LIU Di ZHANG Yingqi YU Tianyuan LIU Zhifeng JIAO Yi WANG Hourong XU Yajing GUAN Qian CHEN Lulu HU Hui 
the National Natural Science Foundation of China:to Explore the Antipyretic Effects and Mechanism of the“Reducing Fever Six Methods”Technique on Infant Rabbits with Fever from the Peripheral TLR4/NF-kB Signaling Pathway to the Central Positive and Negative Mediators(No.81873392)。
OBJECTIVE:To investigate the effect of Tuina on the plasma metabolites of lipopolysaccharide-induced febrile in infant rabbits.METHODS:Twenty-four infant New Zealand rabbits were selected and randomly divided into thr...
关键词：FEVER PEDIATRICS metabolomics LIPOPOLYSACCHARIDES RIBOFLAVIN glycine Tuina therapy 
Activating transcription factor 4 protects mice against sepsis-induced intestinal injury by regulating gut-resident macrophages differentiation被引量：3
《Chinese Medical Journal》2022年第21期2585-2595,共11页Zhenliang Wen Xi Xiong Dechang Chen Lujing Shao Xiaomeng Tang Xuan Shen Sheng Zhang Sisi Huang Lidi Zhang Yizhu Chen Yucai Zhang Chunxia Wang Jiao Liu 
National Natural Science Foundation of China(Nos. 82172152, 81873944, 82172154, 81971869, 82171729);Natural Science Foundation of Shanghai(No.19ZR1442500);Research Fund of Ruijin Hospital North Affiliated to Shanghai Jiao Tong University School of Medicine(No.2020ZY11)
Background: Gut-resident macrophages (gMacs) supplemented by monocytes-to-gMacs differentiation play a critical role in maintaining intestinal homeostasis. Activating transcription factor 4 (ATF4) is involved in immun...
关键词：Activating transcription factor 4 Mice LIPOPOLYSACCHARIDES MONOCYTES Leukocytes mononuclear Cell differentiation MACROPHAGES Sepsis Homeostasis gMacs Intestinal injury 
Yajieshaba prevents lipopolysaccharide-induced intestinal barrier injury via anti-inflammatory and anti-apoptosis被引量：1
《Journal of Traditional Chinese Medicine》2022年第5期707-714,共8页YANG Liping YU Xinglin ZHANG Chao CHEN Pu DUAN Xiaohua() 
Supported by Grant from the Scientific Research Project of Yunnan Provincial Hospital of Traditional Chinese Medicine:Protective Effect and Mechanism of Yajie Prescription on Intestinal Mucosal Barrier (No. 2015DYYJ101);Yunnan Provincial Science and Technology Department-Applied Basic Research Joint Special Funds of Yunnan University of Traditional Chinese Medicine:Study on the Protective Effect and Mechanism of the Dai Medicine"Yajieshaba"on Intestinal Mucosal Barrier in Food Allergic Mice (No. 2017FF116-026)。
OBJECTIVE: To investigate the protective effect of Yajieshaba(YJSB) on the intestinal barrier dysfunction induced by lipopolysaccharide(LPS).METHODS: C57BL/6 mice and rat intestinal epithelial cells were treated with ...
关键词：INFLAMMATION apoptosis LIPOPOLYSACCHARIDES Yajieshaba intestinal barrier function 
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