supported by the Youth Fund of the National Natural Science Foundation of China(32200345);China Postdoctoral Science Foundation(2022M710878);the National Natural Science Foundation of China(32270453,32270442,31772448);the Key Project of the National Natural Science Foundation of China(32030011);the PI Project of Southern Marine Science and Engineering Guangdong Laboratory(Guangzhou)(GML2021GD0805)。
Jerboas is a lineage of small rodents displaying atypical mouse-like morphology with elongated strong hindlimbs and short forelimbs.They have evolved obligate bipedal saltation and acute senses,and been well-adapted t...
supported by ISPRO-Istituto per lo Studio,la Prevenzione e la Rete Oncologica(institutional funding to L.P.);It was also partially supported by AIRC-Associazione Italiana Ricerca sul Cancro(IG#25694 to L.P.);P.P.P.has been supported by the Renown Foundation and the PTEN Research Foundation.Cartoons created with BioRender.com.
The advent of high-throughput sequencing uncovered that our genome is pervasively transcribed into RNAs that are seemingly not translated into proteins.It was also found that non-coding RNA transcripts outnumber canon...
Long-range interactions between regulatory elements and gene promoters play key roles in transcriptional regulation.The vast majority of interactions are uncharted,constituting a major missing link in understanding ge...
supported by the National Natural Science Foundation of China(82171836);the 1·3·5 project for disciplines of excellence,West China Hospital,Sichuan University(ZYJC20002).
The application of whole genome sequencing is expanding in clinical diagnostics across various genetic disorders, and the significance of non-coding variants in penetrant diseases is increasingly being demonstrated. T...
supported by the National Natural Science Foundation of China (32022006);the Program for Guangdong"ZhuJiang"Innovation Teams (2019ZT08N628);the Agricultural Science and Technology Innovation Program (ASTIP) (CAAS-XTCX2016001);the special funds for science technology innovation and industrial development of Shenzhen Dapeng New District (PT202101-01);supported by the National Natural Science Foundation of China (32070250);the Natural Science Foundation of Guangdong Province (2020A1515011030);the open research project of"Cross-Cooperative Team"of the Germplasm Bank of Wild Species,Kunming Institute of Botany,Chinese Academy of Sciences;supported by the Natural Science Foundation of Guangdong Province (2022A1515110240);support was provided by IRD and the Agence Nationale de la Recherche (Project SESAM,2010 BLAN 170801).
Plant root-nodule symbiosis(RNS)with mutualistic nitrogen-fixing bacteria is restricted to a single clade of angiosperms,the Nitrogen-Fixing Nodulation Clade(NFNC),and is best understood in the legume family.Nodulatin...
supported by the National Natural Science Foundation of China(grant number:31571361).
Cis-regulatory elements regulate gene expression and play an essential role in the development and physiology of organisms.Many conserved non-coding sequences(CNSs)function as cis-regulatory elements.They control the ...
the Strategic Priority Research Program of Chinese Academy of Sciences(XDB31000000);the National Natural Science Foundation of China(32220103004,32000296);the Second Tibetan Plateau Scientific Expedition and Research Program(2019QZKK0501);the International Partnership Program of Chinese Academy of Sciences(151751KYSB20190024);the Sichuan Science and Technology Program(2021JDJQ0002)。
Limb loss shows recurrent phenotypic evolution across squamate lineages.Here,based on three de novo-assembled genomes of limbless lizards from different lineages,we showed that divergence of conserved non-coding eleme...
the National Natural Science Foundation of China(81788101,32100104);the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(2021-I2M-1022);the CAMS Endowment Fund(2021-CAMS-JZ001);the Overseas Expertise Introduction Center for Discipline Innovation(“111Center”)(BP0820029)。
Dear Editor,During the construction and analysis of the Bencao(herbal)small RNA(s RNA)Atlas,the fact that many s RNAs from the human genome are present in the Bencao(herbal)database attracted our attention(Cao et al.,...
supported by the National Natural Science Foundation of China(grants 32070627 and 31960138 to D.W.,31800224 and 32160070 to R.H.,and 31788103 to X.C.);the Chinese Academy of Sciences(Strategic Priority Research Program XDB27030201 to X.C.);the Natural Science Foundation of Jiangxi Province(grant 20171ACB20001 to D.W.).
Tens of thousands of long non-coding RNAs have been uncovered in plants,but few of them have been comprehensively studied for their biological function and molecular mechanism of their mode of action.Here,we show that...
funded by the Swedish Research Council(2018-03926);Carl Trygger Foundation(20:224).
Non-coding transcription is present in all eukaryotic genomes,but we lack fundamental knowledge about its importance for an organism’s ability to develop properly.In plants,emerging evidence highlights the essential ...