supported by grant from the General Project and Invention of Prince of Songkla University(SCI600421S),Graduate School of Prince of Songkla University,Songkhla,Thailand.
Objective:To evaluate the effect of standardized extract of Centella asiatica ECa 233 on inflammatory mediator production through cyclooxygenase-2(COX-2),extracellular signal-regulated kinase 1/2(ERK1/2)and nuclear fa...
Supported by Hangzhou Health Technology Project:Study of the Relationship Between Mitofusin 2 And Cyclosporine A Nephropathy(No.2018A52);National Natural Science Foundation of China:Study on Mechanism of Centella Asiatica Compound in the Treatment of Iga Nephropathy by Regulating Mesangial Cell Proliferation via Mitofusin 2(No.81373631)
OBJECTIVE:To investigate the effect of mitofusin 2 (Mfn2) and its downstream signaling pathway on glomerular mesangial cells (GMCs) proliferation in IgA nephropathy (IgAN),as well as the mechanism of action of Jixueca...
Objective:To investigate the antifertility properties ofCentella asiatica L. ethanolic extract and identify the sperm proteomic changes in treated male rats.Methods: A total of 32 male Sprague-Dawley rats were divided...
It is generally recognized that Caucasians and Asians have different skin aging features. The aim of this study was to develop a facial wrinkle grading scale for Chinese women. Standard photographs were taken of 242 C...
Centella asiatica (Linn.) belongs to the family of Apiaceae(Umbeliferae). It has been widely used for traditional medicine, especially for wound healing, anti-inflammatory,antipsoriatic, antiulcer, antibacterial and a...
Supported by DPP-SPP Medical Faculty of Brawijaya University and LPPM Brawijaya University with Grant No.023.04.2.414989/2014
Objective: To observe the effects of Centella asiatica(C. asiatica) methanolic extract on a-synuclein aggregation and its expression in rotenone-exposed zebra fish.Methods: Zebra fish(Danio rerio) were exposed to 5 m ...
The accumulation of amyloid β peptide 1 - 42 (Aβ1-42) in the brain of Alzheimer’s disease (AD) patients is known to be associated with neurodegeneration and memory impairment. More recently, we reported that madeca...
The project supported by Directorate General of Higher Education,Ministry of Education and Research Technology of Indonesia,Through Fundamental Research grant 2014
OBJECTIVE To investigate the motility,dopamine,serotonin and pro-BDNF level of Centella asiatica(CA)comparable to the combination of levodopa and benzerazid HCL on zebrafish model Parkinson′s.METHODS Rotenone 5μg·L...
Antimicrobial agents such as bavistin, cefotaxime and kanamycin were evaluated for their effects on the rapid shoot regeneration from nodal explants of Centella asiatica (L.). Filter sterilized bavistin (250 mg/L) was...